IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4+ T cell responses

IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4+ T cell responses

Abstract Mast cells are potent mediators of allergy and asthma, yet their role in regulating adaptive immunity remains ambiguous. On the surface of mast cells, the crosslinking of IgE bound to FcεRI by a specific antigen recognized by that IgE triggers the release of immune mediators such as histami...

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Autores principales: Binh L. Phong, Shaina J. D’Souza, Robin L. Baudier, Eric Wu, Victoria E. Immethun, David L. Bauer, James B. McLachlan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/32e9ca69d1884b0986078bf9e4464819
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