Pregnancy-induced effects on memory B-cell development in multiple sclerosis

Pregnancy-induced effects on memory B-cell development in multiple sclerosis

Abstract In MS, pathogenic memory B cells infiltrate the brain and develop into antibody-secreting cells. Chemokine receptors not only define their brain-infiltrating capacity, but also assist in their maturation in germinal centers. How this corresponds to pregnancy, as a naturally occurring modifi...

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Autores principales: Malou Janssen, Liza Rijvers, Steven C. Koetzier, Annet F. Wierenga-Wolf, Marie-José Melief, Jamie van Langelaar, Tessel F. Runia, Christianne J. M. de Groot, Rinze Neuteboom, Joost Smolders, Marvin M. van Luijn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/32ebd22e76a44d9db5b13828cd756796
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