Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure

The skin’s tanning response to sun exposure shows great interindividual variability. Here, Visconti et al. perform a genome-wide association study for ease of skin tanning and identify 20 genetic loci, ten of which had not previously been associated with pigmentation-related traits.

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Autores principales: Alessia Visconti, David L. Duffy, Fan Liu, Gu Zhu, Wenting Wu, Yan Chen, Pirro G. Hysi, Changqing Zeng, Marianna Sanna, Mark M. Iles, Peter A. Kanetsky, Florence Demenais, Merel A. Hamer, Andre G. Uitterlinden, M. Arfan Ikram, Tamar Nijsten, Nicholas G. Martin, Manfred Kayser, Tim D. Spector, Jiali Han, Veronique Bataille, Mario Falchi
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/33077312c7374160b11383064ec8d844
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spelling oai:doaj.org-article:33077312c7374160b11383064ec8d8442021-12-02T14:39:08ZGenome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure10.1038/s41467-018-04086-y2041-1723https://doaj.org/article/33077312c7374160b11383064ec8d8442018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04086-yhttps://doaj.org/toc/2041-1723The skin’s tanning response to sun exposure shows great interindividual variability. Here, Visconti et al. perform a genome-wide association study for ease of skin tanning and identify 20 genetic loci, ten of which had not previously been associated with pigmentation-related traits.Alessia ViscontiDavid L. DuffyFan LiuGu ZhuWenting WuYan ChenPirro G. HysiChangqing ZengMarianna SannaMark M. IlesPeter A. KanetskyFlorence DemenaisMerel A. HamerAndre G. UitterlindenM. Arfan IkramTamar NijstenNicholas G. MartinManfred KayserTim D. SpectorJiali HanVeronique BatailleMario FalchiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alessia Visconti
David L. Duffy
Fan Liu
Gu Zhu
Wenting Wu
Yan Chen
Pirro G. Hysi
Changqing Zeng
Marianna Sanna
Mark M. Iles
Peter A. Kanetsky
Florence Demenais
Merel A. Hamer
Andre G. Uitterlinden
M. Arfan Ikram
Tamar Nijsten
Nicholas G. Martin
Manfred Kayser
Tim D. Spector
Jiali Han
Veronique Bataille
Mario Falchi
Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
description The skin’s tanning response to sun exposure shows great interindividual variability. Here, Visconti et al. perform a genome-wide association study for ease of skin tanning and identify 20 genetic loci, ten of which had not previously been associated with pigmentation-related traits.
format article
author Alessia Visconti
David L. Duffy
Fan Liu
Gu Zhu
Wenting Wu
Yan Chen
Pirro G. Hysi
Changqing Zeng
Marianna Sanna
Mark M. Iles
Peter A. Kanetsky
Florence Demenais
Merel A. Hamer
Andre G. Uitterlinden
M. Arfan Ikram
Tamar Nijsten
Nicholas G. Martin
Manfred Kayser
Tim D. Spector
Jiali Han
Veronique Bataille
Mario Falchi
author_facet Alessia Visconti
David L. Duffy
Fan Liu
Gu Zhu
Wenting Wu
Yan Chen
Pirro G. Hysi
Changqing Zeng
Marianna Sanna
Mark M. Iles
Peter A. Kanetsky
Florence Demenais
Merel A. Hamer
Andre G. Uitterlinden
M. Arfan Ikram
Tamar Nijsten
Nicholas G. Martin
Manfred Kayser
Tim D. Spector
Jiali Han
Veronique Bataille
Mario Falchi
author_sort Alessia Visconti
title Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
title_short Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
title_full Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
title_fullStr Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
title_full_unstemmed Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure
title_sort genome-wide association study in 176,678 europeans reveals genetic loci for tanning response to sun exposure
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/33077312c7374160b11383064ec8d844
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