Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts
Indels that are commonly found in cancer genomes are characterized by non-random sequence composition and localisation. Here, the authors described a method to investigate transcriptional strand asymmetries and sequence-context specific mechanisms that alter the likelihood of insertions and deletion...
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Auteurs principaux: | Ilias Georgakopoulos-Soares, Gene Koh, Sophie E. Momen, Josef Jiricny, Martin Hemberg, Serena Nik-Zainal |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/330a18a3bad7426cba3f743bc68365db |
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