Optical imaging for breast cancer prescreening

Anuradha Godavarty,1 Suset Rodriguez,1 Young-Jin Jung,2 Stephanie Gonzalez1 1Optical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA; 2Department of Radiological Science, Dongseo University, Busan, South Korea Abstract: Breast cancer prescr...

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Autores principales: Godavarty A, Rodriguez S, Jung YJ, Gonzalez S
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Lenguaje:EN
Publicado: Dove Medical Press 2015
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Acceso en línea:https://doaj.org/article/330ab409c73040b180b454f6d886af18
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spelling oai:doaj.org-article:330ab409c73040b180b454f6d886af182021-12-02T06:29:50ZOptical imaging for breast cancer prescreening1179-1314https://doaj.org/article/330ab409c73040b180b454f6d886af182015-07-01T00:00:00Zhttp://www.dovepress.com/optical-imaging-for-breast-cancer-prescreening-peer-reviewed-article-BCTThttps://doaj.org/toc/1179-1314Anuradha Godavarty,1 Suset Rodriguez,1 Young-Jin Jung,2 Stephanie Gonzalez1 1Optical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA; 2Department of Radiological Science, Dongseo University, Busan, South Korea Abstract: Breast cancer prescreening is carried out prior to the gold standard screening using X-ray mammography and/or ultrasound. Prescreening is typically carried out using clinical breast examination (CBE) or self-breast examinations (SBEs). Since CBE and SBE have high false-positive rates, there is a need for a low-cost, noninvasive, non-radiative, and portable imaging modality that can be used as a prescreening tool to complement CBE/SBE. This review focuses on the various hand-held optical imaging devices that have been developed and applied toward early-stage breast cancer detection or as a prescreening tool via phantom, in vivo, and breast cancer imaging studies. Apart from the various optical devices developed by different research groups, a wide-field fiber-free near-infrared optical scanner has been developed for transillumination-based breast imaging in our Optical Imaging Laboratory. Preliminary in vivo studies on normal breast tissues, with absorption-contrasted targets placed in the intramammary fold, detected targets as deep as 8.8 cm. Future work involves in vivo imaging studies on breast cancer subjects and comparison with the gold standard X-ray mammography approach. Keywords: diffuse optical imaging, near-infrared, hand-held devices, breast cancer, prescreening, early detection Godavarty ARodriguez SJung YJGonzalez SDove Medical PressarticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBreast Cancer: Targets and Therapy, Vol 2015, Iss default, Pp 193-209 (2015)
institution DOAJ
collection DOAJ
language EN
topic Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
spellingShingle Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Godavarty A
Rodriguez S
Jung YJ
Gonzalez S
Optical imaging for breast cancer prescreening
description Anuradha Godavarty,1 Suset Rodriguez,1 Young-Jin Jung,2 Stephanie Gonzalez1 1Optical Imaging Laboratory, Department of Biomedical Engineering, Florida International University, Miami, FL, USA; 2Department of Radiological Science, Dongseo University, Busan, South Korea Abstract: Breast cancer prescreening is carried out prior to the gold standard screening using X-ray mammography and/or ultrasound. Prescreening is typically carried out using clinical breast examination (CBE) or self-breast examinations (SBEs). Since CBE and SBE have high false-positive rates, there is a need for a low-cost, noninvasive, non-radiative, and portable imaging modality that can be used as a prescreening tool to complement CBE/SBE. This review focuses on the various hand-held optical imaging devices that have been developed and applied toward early-stage breast cancer detection or as a prescreening tool via phantom, in vivo, and breast cancer imaging studies. Apart from the various optical devices developed by different research groups, a wide-field fiber-free near-infrared optical scanner has been developed for transillumination-based breast imaging in our Optical Imaging Laboratory. Preliminary in vivo studies on normal breast tissues, with absorption-contrasted targets placed in the intramammary fold, detected targets as deep as 8.8 cm. Future work involves in vivo imaging studies on breast cancer subjects and comparison with the gold standard X-ray mammography approach. Keywords: diffuse optical imaging, near-infrared, hand-held devices, breast cancer, prescreening, early detection 
format article
author Godavarty A
Rodriguez S
Jung YJ
Gonzalez S
author_facet Godavarty A
Rodriguez S
Jung YJ
Gonzalez S
author_sort Godavarty A
title Optical imaging for breast cancer prescreening
title_short Optical imaging for breast cancer prescreening
title_full Optical imaging for breast cancer prescreening
title_fullStr Optical imaging for breast cancer prescreening
title_full_unstemmed Optical imaging for breast cancer prescreening
title_sort optical imaging for breast cancer prescreening
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/330ab409c73040b180b454f6d886af18
work_keys_str_mv AT godavartya opticalimagingforbreastcancerprescreening
AT rodriguezs opticalimagingforbreastcancerprescreening
AT jungyj opticalimagingforbreastcancerprescreening
AT gonzalezs opticalimagingforbreastcancerprescreening
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