Fast and powerful genome wide association of dense genetic data with high dimensional imaging phenotypes

Código QR

Fast and powerful genome wide association of dense genetic data with high dimensional imaging phenotypes

Genome-wide association studies (GWAS) of neuroimaging data pose a significant computational burden because of the need to correct for multiple testing in both the genetic and the imaging data. Here, Ganjgahi et al. develop WLS-REML which significantly reduces computation running times in brain imag...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Habib Ganjgahi, Anderson M. Winkler, David C. Glahn, John Blangero, Brian Donohue, Peter Kochunov, Thomas E. Nichols
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3315ced0f5074d3a9344c50e4a584c44
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Powerful turbidity currents driven by dense basal layers
por: Charles K. Paull, et al.
Publicado: (2018)

Detection of selection signatures in farmed coho salmon (Oncorhynchus kisutch) using dense genome-wide information
por: M. E. López, et al.
Publicado: (2021)

Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data
por: Nicole M. Warrington, et al.
Publicado: (2021)

Development of an ultra-dense genetic map of the sunflower genome based on single-feature polymorphisms.
por: John E Bowers, et al.
Publicado: (2012)

Minimal control power of controlled dense coding and genuine tripartite entanglement
por: Changhun Oh, et al.
Publicado: (2017)

Controlling for background genetic effects using polygenic scores improves the power of genome-wide association studies
por: Declan Bennett, et al.
Publicado: (2021)

Fast principal component analysis of large-scale genome-wide data.
por: Gad Abraham, et al.
Publicado: (2014)

Automatic 3D dense phenotyping provides reliable and accurate shape quantification of the human mandible
por: Pieter-Jan Verhelst, et al.
Publicado: (2021)

Multi-phenotype genome-wide association studies of the Norfolk Island isolate implicate pleiotropic loci involved in chronic kidney disease
por: Ngan K. Tran, et al.
Publicado: (2021)

Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision
por: James A Watson, et al.
Publicado: (2021)

Prediction of disease and phenotype associations from genome-wide association studies.
por: Stephanie N Lewis, et al.
Publicado: (2011)

A SUPER powerful method for genome wide association study.
por: Qishan Wang, et al.
Publicado: (2014)

Dense and accurate whole-chromosome haplotyping of individual genomes
por: David Porubsky, et al.
Publicado: (2017)

Approximate conditional phenotype analysis based on genome wide association summary statistics
por: Peitao Wu, et al.
Publicado: (2021)

Discovering genetic interactions bridging pathways in genome-wide association studies
por: Gang Fang, et al.
Publicado: (2019)

Genomic architecture and prediction of censored time-to-event phenotypes with a Bayesian genome-wide analysis
por: Sven E. Ojavee, et al.
Publicado: (2021)

A Fast Terminal Matching Method for Interference Coordination Based on Wavelet Transform and Graph Theory in Ultra-Dense Multi-Cell Scenarios
por: Junxiang Gou, et al.
Publicado: (2021)

Human-interpretable image features derived from densely mapped cancer pathology slides predict diverse molecular phenotypes
por: James A. Diao, et al.
Publicado: (2021)

Genome-wide association study of pancreatic fat: The Multiethnic Cohort Adiposity Phenotype Study.
por: Samantha A Streicher, et al.
Publicado: (2021)

A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
por: Yanjun Guo, et al.
Publicado: (2020)

Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping
por: Jiazhang Lian, et al.
Publicado: (2019)

Insights into the genetic history of French cattle from dense SNP data on 47 worldwide breeds.
por: Mathieu Gautier, et al.
Publicado: (2010)

Low dimensional nanostructures of fast ion conducting lithium nitride
por: Nuria Tapia-Ruiz, et al.
Publicado: (2020)

NIBBS-search for fast and accurate prediction of phenotype-biased metabolic systems.
por: Matthew C Schmidt, et al.
Publicado: (2012)

Fast wide-volume functional imaging of engineered in vitro brain tissues
por: G. Palazzolo, et al.
Publicado: (2017)

An extreme-phenotype genome‐wide association study identifies candidate cannabinoid pathway genes in Cannabis
por: Matthew T. Welling, et al.
Publicado: (2020)

Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen.
por: Apichat Suratanee, et al.
Publicado: (2014)

Termite’s Twisted Mandible Presents Fast, Powerful, and Precise Strikes
por: Kuan-Chih Kuan, et al.
Publicado: (2020)

A genome-wide survey of genetic instability by transposition in Drosophila hybrids.
por: Doris Vela, et al.
Publicado: (2014)

Dense cellular segmentation for EM using 2D–3D neural network ensembles
por: Matthew D. Guay, et al.
Publicado: (2021)

A genome wide survey of SNP variation reveals the genetic structure of sheep breeds.
por: James W Kijas, et al.
Publicado: (2009)

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
por: David M. Howard, et al.
Publicado: (2018)

Genome-wide comparative analyses of correlated and uncorrelated phenotypes identify major pleiotropic variants in dairy cattle
por: Ruidong Xiang, et al.
Publicado: (2017)

Parallel power posterior analyses for fast computation of marginal likelihoods in phylogenetics
por: Sebastian Höhna, et al.
Publicado: (2021)

An overview of the genetic structure within the Italian population from genome-wide data.
por: Cornelia Di Gaetano, et al.
Publicado: (2012)

Emergent genome-wide control in wildtype and genetically mutated lipopolysaccarides-stimulated macrophages.
por: Masa Tsuchiya, et al.
Publicado: (2009)

Results of genome-wide analyses on neurodevelopmental phenotypes at four-year follow-up following cardiac surgery in infancy.
por: Daniel S Kim, et al.
Publicado: (2012)

Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts
por: Elizabeth T. Cirulli, et al.
Publicado: (2020)

Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
por: David M. Howard, et al.
Publicado: (2018)

Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms.
por: Camille Jung, et al.
Publicado: (2012)