Gene therapy for neuropathic pain by silencing of TNF-α expression with lentiviral vectors targeting the dorsal root ganglion in mice.
Neuropathic pain can be a debilitating condition. Many types of drugs that have been used to treat neuropathic pain have only limited efficacy. Recent studies indicate that pro-inflammatory mediators including tumor necrosis factor α (TNF-α) are involved in the pathogenesis of neuropathic pain. In t...
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Autores principales: | Nobuhiro Ogawa, Hiromichi Kawai, Tomoya Terashima, Hideto Kojima, Kazuhiro Oka, Lawrence Chan, Hiroshi Maegawa |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/3325c598e6a640f992e24aace7e17915 |
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