Carbonic anhydrase inhibitor induces otic hair cell apoptosis via an intrinsic pathway and ER stress in zebrafish larvae

Carbonic anhydrase (CA) catalyzes reversible hydration of CO2 to HCO3− to mediate pH and ion homeostasis. Some chemical pollutants have been reported to have inhibitory effects on fish CA. In this study, we investigated effects of a CA inhibitor ethoxyzolamide (EZA) on neuromasts development during...

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Bibliographic Details
Main Authors: Hiroko Matsumoto, Hisako Miyagi, Nobuhiro Nakamura, Yasuhiro Shiga, Toshihiro Ohta, Shoko Fujiwara, Mikio Tsuzuki
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/332d19bc5d6d4be58741166b802e7a2d
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