Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report

Wei Qin, 1,* Xiao Wang, 1,* Jing Yang, 2 Wenli Hu 1 1Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of China; 2Department of Hyperbaric Oxygen, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People...

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Autores principales:	Qin W, Wang X, Yang J, Hu W
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	autoimmune encephalitis anti-gabab receptor small cell lung cancer Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/333c28e3916d4cd5ae5ccd8d7ebaceae
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spelling	oai:doaj.org-article:333c28e3916d4cd5ae5ccd8d7ebaceae2021-12-02T04:59:38ZCoexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report1178-1998https://doaj.org/article/333c28e3916d4cd5ae5ccd8d7ebaceae2020-02-01T00:00:00Zhttps://www.dovepress.com/coexistence-of-anti-sox1-and-anti-gabab-receptor-antibodies-with-autoi-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Wei Qin, 1,* Xiao Wang, 1,* Jing Yang, 2 Wenli Hu 1 1Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of China; 2Department of Hyperbaric Oxygen, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing YangDepartment of Hyperbaric Oxygen, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of ChinaTel +86 1085232005Email jyangu@hotmail.comWenli HuDepartment of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of ChinaTel +86 1085231376Email stroke2019@126.comAbstract: Anti-γ-aminobutyric acid B receptor (anti-GABABR) encephalitis is a rare type of autoimmune encephalitis (AE). Although it responds well to immunomodulating therapy and has favorable prognosis, anti-GABABR AE has often been misdiagnosed as infectious encephalitis. Herein, we present a case of a 59-year-old female with anti-GABABR AE associated with small cell lung cancer (SCLC) that was once misdiagnosed as infectious encephalitis. Our findings increase the awareness that patients presenting with a clinical trial of cognitive impairment, seizures and SCLC may harbor AE. Our case also highlights the importance of anti-SOX1 antibody in the detection of SCLC.Keywords: autoimmune encephalitis, anti-GABAB receptor, small cell lung cancerQin WWang XYang JHu WDove Medical Pressarticleautoimmune encephalitisanti-gabab receptorsmall cell lung cancerGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 15, Pp 171-175 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	autoimmune encephalitis anti-gabab receptor small cell lung cancer Geriatrics RC952-954.6
spellingShingle	autoimmune encephalitis anti-gabab receptor small cell lung cancer Geriatrics RC952-954.6 Qin W Wang X Yang J Hu W Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
description	Wei Qin, 1,* Xiao Wang, 1,* Jing Yang, 2 Wenli Hu 1 1Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of China; 2Department of Hyperbaric Oxygen, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing YangDepartment of Hyperbaric Oxygen, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of ChinaTel +86 1085232005Email jyangu@hotmail.comWenli HuDepartment of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, People’s Republic of ChinaTel +86 1085231376Email stroke2019@126.comAbstract: Anti-γ-aminobutyric acid B receptor (anti-GABABR) encephalitis is a rare type of autoimmune encephalitis (AE). Although it responds well to immunomodulating therapy and has favorable prognosis, anti-GABABR AE has often been misdiagnosed as infectious encephalitis. Herein, we present a case of a 59-year-old female with anti-GABABR AE associated with small cell lung cancer (SCLC) that was once misdiagnosed as infectious encephalitis. Our findings increase the awareness that patients presenting with a clinical trial of cognitive impairment, seizures and SCLC may harbor AE. Our case also highlights the importance of anti-SOX1 antibody in the detection of SCLC.Keywords: autoimmune encephalitis, anti-GABAB receptor, small cell lung cancer
format	article
author	Qin W Wang X Yang J Hu W
author_facet	Qin W Wang X Yang J Hu W
author_sort	Qin W
title	Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_short	Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_full	Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_fullStr	Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_full_unstemmed	Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report
title_sort	coexistence of anti-sox1 and anti-gabab receptor antibodies with autoimmune encephalitis in small cell lung cancer: a case report
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/333c28e3916d4cd5ae5ccd8d7ebaceae
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_version_	1718400880871473152

Coexistence of Anti-SOX1 and Anti-GABAB Receptor Antibodies with Autoimmune Encephalitis in Small Cell Lung Cancer: A Case Report

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