A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii

Apicomplexan parasites such as Toxoplasma gondii possess a tubulin-rich structure called the conoid. Here, Long et al. identify a conoid protein that interacts with motor and structural proteins and is required for structural integrity of the conoid, parasite motility, and host cell invasion.

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Autores principales: Shaojun Long, Bryan Anthony, Lisa L. Drewry, L. David Sibley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/33465d3f02bd4bd9a33944962a813a84
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spelling oai:doaj.org-article:33465d3f02bd4bd9a33944962a813a842021-12-02T15:38:47ZA conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii10.1038/s41467-017-02341-22041-1723https://doaj.org/article/33465d3f02bd4bd9a33944962a813a842017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02341-2https://doaj.org/toc/2041-1723Apicomplexan parasites such as Toxoplasma gondii possess a tubulin-rich structure called the conoid. Here, Long et al. identify a conoid protein that interacts with motor and structural proteins and is required for structural integrity of the conoid, parasite motility, and host cell invasion.Shaojun LongBryan AnthonyLisa L. DrewryL. David SibleyNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shaojun Long
Bryan Anthony
Lisa L. Drewry
L. David Sibley
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
description Apicomplexan parasites such as Toxoplasma gondii possess a tubulin-rich structure called the conoid. Here, Long et al. identify a conoid protein that interacts with motor and structural proteins and is required for structural integrity of the conoid, parasite motility, and host cell invasion.
format article
author Shaojun Long
Bryan Anthony
Lisa L. Drewry
L. David Sibley
author_facet Shaojun Long
Bryan Anthony
Lisa L. Drewry
L. David Sibley
author_sort Shaojun Long
title A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
title_short A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
title_full A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
title_fullStr A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
title_full_unstemmed A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
title_sort conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in toxoplasma gondii
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/33465d3f02bd4bd9a33944962a813a84
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