A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii
Apicomplexan parasites such as Toxoplasma gondii possess a tubulin-rich structure called the conoid. Here, Long et al. identify a conoid protein that interacts with motor and structural proteins and is required for structural integrity of the conoid, parasite motility, and host cell invasion.
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Nature Portfolio
2017
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oai:doaj.org-article:33465d3f02bd4bd9a33944962a813a842021-12-02T15:38:47ZA conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii10.1038/s41467-017-02341-22041-1723https://doaj.org/article/33465d3f02bd4bd9a33944962a813a842017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02341-2https://doaj.org/toc/2041-1723Apicomplexan parasites such as Toxoplasma gondii possess a tubulin-rich structure called the conoid. Here, Long et al. identify a conoid protein that interacts with motor and structural proteins and is required for structural integrity of the conoid, parasite motility, and host cell invasion.Shaojun LongBryan AnthonyLisa L. DrewryL. David SibleyNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q Shaojun Long Bryan Anthony Lisa L. Drewry L. David Sibley A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii |
description |
Apicomplexan parasites such as Toxoplasma gondii possess a tubulin-rich structure called the conoid. Here, Long et al. identify a conoid protein that interacts with motor and structural proteins and is required for structural integrity of the conoid, parasite motility, and host cell invasion. |
format |
article |
author |
Shaojun Long Bryan Anthony Lisa L. Drewry L. David Sibley |
author_facet |
Shaojun Long Bryan Anthony Lisa L. Drewry L. David Sibley |
author_sort |
Shaojun Long |
title |
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii |
title_short |
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii |
title_full |
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii |
title_fullStr |
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii |
title_full_unstemmed |
A conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in Toxoplasma gondii |
title_sort |
conserved ankyrin repeat-containing protein regulates conoid stability, motility and cell invasion in toxoplasma gondii |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/33465d3f02bd4bd9a33944962a813a84 |
work_keys_str_mv |
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