ZIP8 zinc transporter: indispensable role for both multiple-organ organogenesis and hematopoiesis in utero.

Previously this laboratory characterized Slc39a8-encoded ZIP8 as a Zn(2+)/(HCO(3)(-))(2) symporter; yet, the overall physiological importance of ZIP8 at the whole-organism level remains unclear. Herein we describe the phenotype of the hypomorphic Slc39a8(neo/neo) mouse which has retained the neomyci...

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Autores principales: Marina Gálvez-Peralta, Lei He, Lucia F Jorge-Nebert, Bin Wang, Marian L Miller, Bryan L Eppert, Scott Afton, Daniel W Nebert
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/334ad18e679e416c80dd67622b899a9b
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