Mutations in the <named-content content-type="genus-species">Plasmodium falciparum</named-content> Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance

Mutations in the <named-content content-type="genus-species">Plasmodium falciparum</named-content> Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance

ABSTRACT Mutations in the Plasmodium falciparum cyclic amine resistance locus (PfCARL) are associated with parasite resistance to the imidazolopiperazines, a potent class of novel antimalarial compounds that display both prophylactic and transmission-blocking activity, in addition to activity agains...

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Autores principales: Gregory LaMonte, Michelle Yi-Xiu Lim, Melanie Wree, Christin Reimer, Marie Nachon, Victoria Corey, Peter Gedeck, David Plouffe, Alan Du, Nelissa Figueroa, Bryan Yeung, Pablo Bifani, Elizabeth A. Winzeler
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/33570c8df3e44fc5aca76e483b8c7bab
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