An integrative method to decode regulatory logics in gene transcription
Existing transcriptional regulatory networks models fall short of deciphering the cooperation between multiple transcription factors on dynamic gene expression. Here the authors develop an integrative method that combines gene expression and transcription factor-DNA binding data to decode transcript...
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Nature Portfolio
2017
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oai:doaj.org-article:3358677a7c7943d98b13f54618c6ce492021-12-02T15:38:46ZAn integrative method to decode regulatory logics in gene transcription10.1038/s41467-017-01193-02041-1723https://doaj.org/article/3358677a7c7943d98b13f54618c6ce492017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01193-0https://doaj.org/toc/2041-1723Existing transcriptional regulatory networks models fall short of deciphering the cooperation between multiple transcription factors on dynamic gene expression. Here the authors develop an integrative method that combines gene expression and transcription factor-DNA binding data to decode transcription regulatory logics.Bin YanDaogang GuanChao WangJunwen WangBing HeJing QinKenneth R. BohelerAiping LuGe ZhangHailong ZhuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q Bin Yan Daogang Guan Chao Wang Junwen Wang Bing He Jing Qin Kenneth R. Boheler Aiping Lu Ge Zhang Hailong Zhu An integrative method to decode regulatory logics in gene transcription |
description |
Existing transcriptional regulatory networks models fall short of deciphering the cooperation between multiple transcription factors on dynamic gene expression. Here the authors develop an integrative method that combines gene expression and transcription factor-DNA binding data to decode transcription regulatory logics. |
format |
article |
author |
Bin Yan Daogang Guan Chao Wang Junwen Wang Bing He Jing Qin Kenneth R. Boheler Aiping Lu Ge Zhang Hailong Zhu |
author_facet |
Bin Yan Daogang Guan Chao Wang Junwen Wang Bing He Jing Qin Kenneth R. Boheler Aiping Lu Ge Zhang Hailong Zhu |
author_sort |
Bin Yan |
title |
An integrative method to decode regulatory logics in gene transcription |
title_short |
An integrative method to decode regulatory logics in gene transcription |
title_full |
An integrative method to decode regulatory logics in gene transcription |
title_fullStr |
An integrative method to decode regulatory logics in gene transcription |
title_full_unstemmed |
An integrative method to decode regulatory logics in gene transcription |
title_sort |
integrative method to decode regulatory logics in gene transcription |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/3358677a7c7943d98b13f54618c6ce49 |
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