Ischemic heart injury leads to HIF1-dependent differential splicing of CaMK2γ
Abstract Ischemic heart disease is a leading cause of heart failure and hypoxia inducible factor 1 (HIF1) is a key transcription factor in the response to hypoxic injury. Our lab has developed a mouse model in which a mutated, oxygen-stable form of HIF1α (HIF-PPN) can be inducibly expressed in cardi...
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Auteurs principaux: | Allison Lesher Williams, Chad B. Walton, Blake Pinell, Vedbar S. Khadka, Brandyn Dunn, Katie Lee, M. C. Therese Anagaran, Abigail Avelar, Ralph V. Shohet |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/3358c57a1c804a2fa84edf3e2217d1eb |
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