Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions
LncRNAs regulate gene expression via their RNA product and through transcriptional interference. Here, Stojic et al.uncouple these functions by using multiple siRNAs against GNG12-AS1 to show that this lncRNA has a product related role in MET signaling while its transcription modulates DIRAS3 expres...
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Main Authors: | , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/3369c8d0029843a985e6ea32ac2d1c39 |
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