Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease

Abstract Background The interaction between the brain and periphery might play a crucial role in the development of Alzheimer’s disease (AD). Methods Using blood transcriptomic profile data from two independent AD cohorts, we performed expression quantitative trait locus (cis-eQTL) analysis of 29 si...

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Autores principales: Young Ho Park, Jung-Min Pyun, Angela Hodges, Jae-Won Jang, Paula J. Bice, SangYun Kim, Andrew J. Saykin, Kwangsik Nho, for the AddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/336e0a70dfa542ebbdfc9af946dc5ecc
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