Lactate sensing mechanisms in arterial chemoreceptor cells

Lactate levels in blood change during hypoxia or exercise, however whether this variable is sensed to evoke adaptive responses is unknown. Here the authors show that oxygen-sensing carotid body cells stimulated by hypoxia are also activated by lactate to potentiate a compensatory ventilatory respons...

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Autores principales:	Hortensia Torres-Torrelo, Patricia Ortega-Sáenz, Lin Gao, José López-Barneo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/337a29a5be2d461eb8785176a46319bd
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spelling	oai:doaj.org-article:337a29a5be2d461eb8785176a46319bd2021-12-02T18:33:59ZLactate sensing mechanisms in arterial chemoreceptor cells10.1038/s41467-021-24444-72041-1723https://doaj.org/article/337a29a5be2d461eb8785176a46319bd2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24444-7https://doaj.org/toc/2041-1723Lactate levels in blood change during hypoxia or exercise, however whether this variable is sensed to evoke adaptive responses is unknown. Here the authors show that oxygen-sensing carotid body cells stimulated by hypoxia are also activated by lactate to potentiate a compensatory ventilatory response.Hortensia Torres-TorreloPatricia Ortega-SáenzLin GaoJosé López-BarneoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hortensia Torres-Torrelo Patricia Ortega-Sáenz Lin Gao José López-Barneo Lactate sensing mechanisms in arterial chemoreceptor cells
description	Lactate levels in blood change during hypoxia or exercise, however whether this variable is sensed to evoke adaptive responses is unknown. Here the authors show that oxygen-sensing carotid body cells stimulated by hypoxia are also activated by lactate to potentiate a compensatory ventilatory response.
format	article
author	Hortensia Torres-Torrelo Patricia Ortega-Sáenz Lin Gao José López-Barneo
author_facet	Hortensia Torres-Torrelo Patricia Ortega-Sáenz Lin Gao José López-Barneo
author_sort	Hortensia Torres-Torrelo
title	Lactate sensing mechanisms in arterial chemoreceptor cells
title_short	Lactate sensing mechanisms in arterial chemoreceptor cells
title_full	Lactate sensing mechanisms in arterial chemoreceptor cells
title_fullStr	Lactate sensing mechanisms in arterial chemoreceptor cells
title_full_unstemmed	Lactate sensing mechanisms in arterial chemoreceptor cells
title_sort	lactate sensing mechanisms in arterial chemoreceptor cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/337a29a5be2d461eb8785176a46319bd
work_keys_str_mv	AT hortensiatorrestorrelo lactatesensingmechanismsinarterialchemoreceptorcells AT patriciaortegasaenz lactatesensingmechanismsinarterialchemoreceptorcells AT lingao lactatesensingmechanismsinarterialchemoreceptorcells AT joselopezbarneo lactatesensingmechanismsinarterialchemoreceptorcells
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Lactate sensing mechanisms in arterial chemoreceptor cells

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