Efficient and selective N-alkylation of amines with alcohols catalysed by manganese pincer complexes

Hydrogen borrowing is an attractive method for C-N bond formation - avoiding multiple alkylation products and reducing waste - but often is carried out with noble metals. Here the authors show that a manganese catalyst allows the selective N-alkylation of amines with alcohols.

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Bibliographic Details
Main Authors: Saravanakumar Elangovan, Jacob Neumann, Jean-Baptiste Sortais, Kathrin Junge, Christophe Darcel, Matthias Beller
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/337ca5d76b314e3fb110d3242a4df67e
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