Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?

The use of opioids in acute pulmonary oedema is considered standard therapy by many physicians. The immediate relieving effect of morphine on the key symptomatic discomfort associated with acute heart failure, dyspnoea, facilitated the categorisation of morphine as a beneficial treatment in this set...

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Autores principales:	Oren Caspi, Doron Aronson
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2020
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/337d6376502443c9b430a2c48db5d63c
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spelling	oai:doaj.org-article:337d6376502443c9b430a2c48db5d63c2021-12-04T16:03:20ZMorphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?10.15420/cfr.2019.222057-75592057-7540https://doaj.org/article/337d6376502443c9b430a2c48db5d63c2020-07-01T00:00:00Zhttps://www.cfrjournal.com/articleindex/cfr.2019.22https://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559The use of opioids in acute pulmonary oedema is considered standard therapy by many physicians. The immediate relieving effect of morphine on the key symptomatic discomfort associated with acute heart failure, dyspnoea, facilitated the categorisation of morphine as a beneficial treatment in this setting. During the last decade, several retrospective studies raised concerns regarding the safety and efficacy of morphine in the setting of acute heart failure. In this article, the physiological effects of morphine on the cardiovascular and respiratory systems are summarised, as well as the potential clinical benefits and risks associated with morphine therapy. Finally, the reported clinical outcomes and adverse event profiles from recent observational studies are discussed, as well as future perspectives and potential alternatives to morphine in the setting of acute heart failure.Oren CaspiDoron AronsonRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 6, Iss , Pp - (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Oren Caspi Doron Aronson Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?
description	The use of opioids in acute pulmonary oedema is considered standard therapy by many physicians. The immediate relieving effect of morphine on the key symptomatic discomfort associated with acute heart failure, dyspnoea, facilitated the categorisation of morphine as a beneficial treatment in this setting. During the last decade, several retrospective studies raised concerns regarding the safety and efficacy of morphine in the setting of acute heart failure. In this article, the physiological effects of morphine on the cardiovascular and respiratory systems are summarised, as well as the potential clinical benefits and risks associated with morphine therapy. Finally, the reported clinical outcomes and adverse event profiles from recent observational studies are discussed, as well as future perspectives and potential alternatives to morphine in the setting of acute heart failure.
format	article
author	Oren Caspi Doron Aronson
author_facet	Oren Caspi Doron Aronson
author_sort	Oren Caspi
title	Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?
title_short	Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?
title_full	Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?
title_fullStr	Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?
title_full_unstemmed	Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?
title_sort	morphine in the setting of acute heart failure: do the risks outweigh the benefits?
publisher	Radcliffe Medical Media
publishDate	2020
url	https://doaj.org/article/337d6376502443c9b430a2c48db5d63c
work_keys_str_mv	AT orencaspi morphineinthesettingofacuteheartfailuredotherisksoutweighthebenefits AT doronaronson morphineinthesettingofacuteheartfailuredotherisksoutweighthebenefits
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Morphine in the Setting of Acute Heart Failure: Do the Risks Outweigh the Benefits?

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