Osteomimicry of mammary adenocarcinoma cells in vitro; increased expression of bone matrix proteins and proliferation within a 3D collagen environment.
Bone is the most common site of metastasis for breast cancer, however the reasons for this remain unclear. We hypothesise that under certain conditions mammary cells possess osteomimetic capabilities that may allow them to adapt to, and flourish within, the bone microenvironment. Mammary cells are k...
Guardado en:
Autores principales: | Rachel F Cox, Allan Jenkinson, Kerstin Pohl, Fergal J O'Brien, Maria P Morgan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3385219dc4f945ea8f24ea6af0ca8e25 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
por: B. Buchmann, et al.
Publicado: (2021) -
Early Proliferation of Bone Marrow Mononuclear Cells on Collagen Membrane, Bone Graft and Tooth Cementum
por: Milagres,Débora, et al.
Publicado: (2009) -
Collagen molecular phenotypic switch between non-neoplastic and neoplastic canine mammary tissues
por: Masahiko Terajima, et al.
Publicado: (2021) -
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
por: Hou-Fu Guo, et al.
Publicado: (2021) -
Canine mammary cancer tumour behaviour and patient survival time are associated with collagen fibre characteristics
por: Ana P. V. Garcia, et al.
Publicado: (2021)