In vivo analysis of protein crowding within the nuclear pore complex in interphase and mitosis

Abstract The central channel of the nuclear pore complex (NPC) is occupied by non-structured polypeptides with a high content of Phe-Gly (FG) motifs. This protein-rich environment functions as an entropic barrier that prevents the passage of molecules, as well as the binding sites for karyopherins,...

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Autores principales: Hide A. Konishi, Suguru Asai, Tomonobu M. Watanabe, Shige H. Yoshimura
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/33865ec1dc2c427a9a46685fa3c53f6c
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