Psychosurgery for schizophrenia: history and perspectives

Matheus Schmidt Soares, Wellingson Silva Paiva, Eda Z Guertzenstein, Robson Luis Amorim, Luca Silveira Bernardo, Jose Francisco Pereira, Erich Talamoni Fonoff, Manoel Jacobsen Teixeira Division of Neurosurgery, Hospital das Clínicas, University of Sao Paulo Medical School, Sao Paulo, Braz...

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Autores principales: Soares MS, Paiva WS, Guertzenstein EZ, Amorim RL, Bernardo LS, Pereira JF, Fonoff ET, Teixeira MJ
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Publicado: Dove Medical Press 2013
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Acceso en línea:https://doaj.org/article/338cecf7cdb44d9d873c4cacf9931087
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spelling oai:doaj.org-article:338cecf7cdb44d9d873c4cacf99310872021-12-02T00:23:30ZPsychosurgery for schizophrenia: history and perspectives1176-63281178-2021https://doaj.org/article/338cecf7cdb44d9d873c4cacf99310872013-04-01T00:00:00Zhttp://www.dovepress.com/psychosurgery-for-schizophrenia-history-and-perspectives-a12771https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Matheus Schmidt Soares, Wellingson Silva Paiva, Eda Z Guertzenstein, Robson Luis Amorim, Luca Silveira Bernardo, Jose Francisco Pereira, Erich Talamoni Fonoff, Manoel Jacobsen Teixeira Division of Neurosurgery, Hospital das Clínicas, University of Sao Paulo Medical School, Sao Paulo, Brazil Abstract: Following the early studies of Moniz and Lima, psychosurgery had considerable scientific credibility until the advent of modern antipsychotics in the mid 1950s. Thereafter, psychosurgery was almost abandoned in large medical centers as a common treatment for schizophrenia, although is still used for some affective and anxiety disorders. We reviewed relevant papers cited in the Medline/Index Medicus, Cochrane, and Scielo databases from 1930 to 2012. In our review of the literature, we show from recent studies that there are still many patients with schizophrenia who have serious deficits even after being treated with current noninvasive therapies. The value of psychosurgery remains controversial. There are no data available to support the use of stereotactic procedures for schizophrenia. Well designed controlled trials are needed to establish the effectiveness of psychosurgery in patients with schizophrenia. Keywords: psychosurgery, schizophrenia, treatment, stereotactic techniquesSoares MSPaiva WSGuertzenstein EZAmorim RLBernardo LSPereira JFFonoff ETTeixeira MJDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 509-515 (2013)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Soares MS
Paiva WS
Guertzenstein EZ
Amorim RL
Bernardo LS
Pereira JF
Fonoff ET
Teixeira MJ
Psychosurgery for schizophrenia: history and perspectives
description Matheus Schmidt Soares, Wellingson Silva Paiva, Eda Z Guertzenstein, Robson Luis Amorim, Luca Silveira Bernardo, Jose Francisco Pereira, Erich Talamoni Fonoff, Manoel Jacobsen Teixeira Division of Neurosurgery, Hospital das Clínicas, University of Sao Paulo Medical School, Sao Paulo, Brazil Abstract: Following the early studies of Moniz and Lima, psychosurgery had considerable scientific credibility until the advent of modern antipsychotics in the mid 1950s. Thereafter, psychosurgery was almost abandoned in large medical centers as a common treatment for schizophrenia, although is still used for some affective and anxiety disorders. We reviewed relevant papers cited in the Medline/Index Medicus, Cochrane, and Scielo databases from 1930 to 2012. In our review of the literature, we show from recent studies that there are still many patients with schizophrenia who have serious deficits even after being treated with current noninvasive therapies. The value of psychosurgery remains controversial. There are no data available to support the use of stereotactic procedures for schizophrenia. Well designed controlled trials are needed to establish the effectiveness of psychosurgery in patients with schizophrenia. Keywords: psychosurgery, schizophrenia, treatment, stereotactic techniques
format article
author Soares MS
Paiva WS
Guertzenstein EZ
Amorim RL
Bernardo LS
Pereira JF
Fonoff ET
Teixeira MJ
author_facet Soares MS
Paiva WS
Guertzenstein EZ
Amorim RL
Bernardo LS
Pereira JF
Fonoff ET
Teixeira MJ
author_sort Soares MS
title Psychosurgery for schizophrenia: history and perspectives
title_short Psychosurgery for schizophrenia: history and perspectives
title_full Psychosurgery for schizophrenia: history and perspectives
title_fullStr Psychosurgery for schizophrenia: history and perspectives
title_full_unstemmed Psychosurgery for schizophrenia: history and perspectives
title_sort psychosurgery for schizophrenia: history and perspectives
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/338cecf7cdb44d9d873c4cacf9931087
work_keys_str_mv AT soaresms psychosurgeryforschizophreniahistoryandperspectives
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AT amorimrl psychosurgeryforschizophreniahistoryandperspectives
AT bernardols psychosurgeryforschizophreniahistoryandperspectives
AT pereirajf psychosurgeryforschizophreniahistoryandperspectives
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