Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis

Using single-cell and spatial transcriptomics in chicken hearts, here, the authors generate a census of cellular interactions from early to late four-chambered heart stage, identifying a distinct epicardial-mesenchymal cell population with a migratory phenotype.

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Autores principales: Madhav Mantri, Gaetano J. Scuderi, Roozbeh Abedini-Nassab, Michael F. Z. Wang, David McKellar, Hao Shi, Benjamin Grodner, Jonathan T. Butcher, Iwijn De Vlaminck
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/338f47e3c52848c0b76ccd9e5670ffa4
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spelling oai:doaj.org-article:338f47e3c52848c0b76ccd9e5670ffa42021-12-02T16:30:42ZSpatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis10.1038/s41467-021-21892-z2041-1723https://doaj.org/article/338f47e3c52848c0b76ccd9e5670ffa42021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21892-zhttps://doaj.org/toc/2041-1723Using single-cell and spatial transcriptomics in chicken hearts, here, the authors generate a census of cellular interactions from early to late four-chambered heart stage, identifying a distinct epicardial-mesenchymal cell population with a migratory phenotype.Madhav MantriGaetano J. ScuderiRoozbeh Abedini-NassabMichael F. Z. WangDavid McKellarHao ShiBenjamin GrodnerJonathan T. ButcherIwijn De VlaminckNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Madhav Mantri
Gaetano J. Scuderi
Roozbeh Abedini-Nassab
Michael F. Z. Wang
David McKellar
Hao Shi
Benjamin Grodner
Jonathan T. Butcher
Iwijn De Vlaminck
Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
description Using single-cell and spatial transcriptomics in chicken hearts, here, the authors generate a census of cellular interactions from early to late four-chambered heart stage, identifying a distinct epicardial-mesenchymal cell population with a migratory phenotype.
format article
author Madhav Mantri
Gaetano J. Scuderi
Roozbeh Abedini-Nassab
Michael F. Z. Wang
David McKellar
Hao Shi
Benjamin Grodner
Jonathan T. Butcher
Iwijn De Vlaminck
author_facet Madhav Mantri
Gaetano J. Scuderi
Roozbeh Abedini-Nassab
Michael F. Z. Wang
David McKellar
Hao Shi
Benjamin Grodner
Jonathan T. Butcher
Iwijn De Vlaminck
author_sort Madhav Mantri
title Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_short Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_full Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_fullStr Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_full_unstemmed Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_sort spatiotemporal single-cell rna sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/338f47e3c52848c0b76ccd9e5670ffa4
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