Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis

Using single-cell and spatial transcriptomics in chicken hearts, here, the authors generate a census of cellular interactions from early to late four-chambered heart stage, identifying a distinct epicardial-mesenchymal cell population with a migratory phenotype.

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Auteurs principaux:	Madhav Mantri, Gaetano J. Scuderi, Roozbeh Abedini-Nassab, Michael F. Z. Wang, David McKellar, Hao Shi, Benjamin Grodner, Jonathan T. Butcher, Iwijn De Vlaminck
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/338f47e3c52848c0b76ccd9e5670ffa4
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id	oai:doaj.org-article:338f47e3c52848c0b76ccd9e5670ffa4
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spelling	oai:doaj.org-article:338f47e3c52848c0b76ccd9e5670ffa42021-12-02T16:30:42ZSpatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis10.1038/s41467-021-21892-z2041-1723https://doaj.org/article/338f47e3c52848c0b76ccd9e5670ffa42021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21892-zhttps://doaj.org/toc/2041-1723Using single-cell and spatial transcriptomics in chicken hearts, here, the authors generate a census of cellular interactions from early to late four-chambered heart stage, identifying a distinct epicardial-mesenchymal cell population with a migratory phenotype.Madhav MantriGaetano J. ScuderiRoozbeh Abedini-NassabMichael F. Z. WangDavid McKellarHao ShiBenjamin GrodnerJonathan T. ButcherIwijn De VlaminckNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Madhav Mantri Gaetano J. Scuderi Roozbeh Abedini-Nassab Michael F. Z. Wang David McKellar Hao Shi Benjamin Grodner Jonathan T. Butcher Iwijn De Vlaminck Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
description	Using single-cell and spatial transcriptomics in chicken hearts, here, the authors generate a census of cellular interactions from early to late four-chambered heart stage, identifying a distinct epicardial-mesenchymal cell population with a migratory phenotype.
format	article
author	Madhav Mantri Gaetano J. Scuderi Roozbeh Abedini-Nassab Michael F. Z. Wang David McKellar Hao Shi Benjamin Grodner Jonathan T. Butcher Iwijn De Vlaminck
author_facet	Madhav Mantri Gaetano J. Scuderi Roozbeh Abedini-Nassab Michael F. Z. Wang David McKellar Hao Shi Benjamin Grodner Jonathan T. Butcher Iwijn De Vlaminck
author_sort	Madhav Mantri
title	Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_short	Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_full	Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_fullStr	Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_full_unstemmed	Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
title_sort	spatiotemporal single-cell rna sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/338f47e3c52848c0b76ccd9e5670ffa4
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Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis

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