ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for colony growth of breast cancer cells.
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Nature Portfolio
2020
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oai:doaj.org-article:338f9cbec70b4e3c819e7803bef5e0102021-12-02T19:02:28ZITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells10.1038/s41467-020-18081-92041-1723https://doaj.org/article/338f9cbec70b4e3c819e7803bef5e0102020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18081-9https://doaj.org/toc/2041-1723The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for colony growth of breast cancer cells.Pedro FuentesMarta SeséPedro J. GuijarroMarta EmperadorSara Sánchez-RedondoHéctor PeinadoStefan HümmerSantiago Ramón y CajalNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Pedro Fuentes Marta Sesé Pedro J. Guijarro Marta Emperador Sara Sánchez-Redondo Héctor Peinado Stefan Hümmer Santiago Ramón y Cajal ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
description |
The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for colony growth of breast cancer cells. |
format |
article |
author |
Pedro Fuentes Marta Sesé Pedro J. Guijarro Marta Emperador Sara Sánchez-Redondo Héctor Peinado Stefan Hümmer Santiago Ramón y Cajal |
author_facet |
Pedro Fuentes Marta Sesé Pedro J. Guijarro Marta Emperador Sara Sánchez-Redondo Héctor Peinado Stefan Hümmer Santiago Ramón y Cajal |
author_sort |
Pedro Fuentes |
title |
ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
title_short |
ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
title_full |
ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
title_fullStr |
ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
title_full_unstemmed |
ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
title_sort |
itgb3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/338f9cbec70b4e3c819e7803bef5e010 |
work_keys_str_mv |
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1718377257411543040 |