ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells

The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for colony growth of breast cancer cells.

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Autores principales: Pedro Fuentes, Marta Sesé, Pedro J. Guijarro, Marta Emperador, Sara Sánchez-Redondo, Héctor Peinado, Stefan Hümmer, Santiago Ramón y Cajal
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/338f9cbec70b4e3c819e7803bef5e010
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spelling oai:doaj.org-article:338f9cbec70b4e3c819e7803bef5e0102021-12-02T19:02:28ZITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells10.1038/s41467-020-18081-92041-1723https://doaj.org/article/338f9cbec70b4e3c819e7803bef5e0102020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18081-9https://doaj.org/toc/2041-1723The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for colony growth of breast cancer cells.Pedro FuentesMarta SeséPedro J. GuijarroMarta EmperadorSara Sánchez-RedondoHéctor PeinadoStefan HümmerSantiago Ramón y CajalNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pedro Fuentes
Marta Sesé
Pedro J. Guijarro
Marta Emperador
Sara Sánchez-Redondo
Héctor Peinado
Stefan Hümmer
Santiago Ramón y Cajal
ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
description The integrin ITGB3 has been described to play an essential role in breast cancer metastasis, but the precise mechanisms remain undefined. Here the authors describe thus far unknown roles of ITGB3 in the uptake of extracellular vesicles, required for colony growth of breast cancer cells.
format article
author Pedro Fuentes
Marta Sesé
Pedro J. Guijarro
Marta Emperador
Sara Sánchez-Redondo
Héctor Peinado
Stefan Hümmer
Santiago Ramón y Cajal
author_facet Pedro Fuentes
Marta Sesé
Pedro J. Guijarro
Marta Emperador
Sara Sánchez-Redondo
Héctor Peinado
Stefan Hümmer
Santiago Ramón y Cajal
author_sort Pedro Fuentes
title ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
title_short ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
title_full ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
title_fullStr ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
title_full_unstemmed ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
title_sort itgb3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/338f9cbec70b4e3c819e7803bef5e010
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