Fungal dissemination is limited by liver macrophage filtration of the blood

Patients with liver diseases are at increased risk of fungal infections. Here the authors show that Kupffer cells are critical for the filtration of fungi out of the blood and thereby for liver-mediated protection against disseminating fungal infection.

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Autores principales: Donglei Sun, Peng Sun, Hongmei Li, Mingshun Zhang, Gongguan Liu, Ashley B. Strickland, Yanli Chen, Yong Fu, Juan Xu, Mohammed Yosri, Yuchen Nan, Hong Zhou, Xiquan Zhang, Meiqing Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Q
Acceso en línea:https://doaj.org/article/3391e8a2cfc74237befa72af3155d7c0
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spelling oai:doaj.org-article:3391e8a2cfc74237befa72af3155d7c02021-12-02T14:39:59ZFungal dissemination is limited by liver macrophage filtration of the blood10.1038/s41467-019-12381-52041-1723https://doaj.org/article/3391e8a2cfc74237befa72af3155d7c02019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12381-5https://doaj.org/toc/2041-1723Patients with liver diseases are at increased risk of fungal infections. Here the authors show that Kupffer cells are critical for the filtration of fungi out of the blood and thereby for liver-mediated protection against disseminating fungal infection.Donglei SunPeng SunHongmei LiMingshun ZhangGongguan LiuAshley B. StricklandYanli ChenYong FuJuan XuMohammed YosriYuchen NanHong ZhouXiquan ZhangMeiqing ShiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Donglei Sun
Peng Sun
Hongmei Li
Mingshun Zhang
Gongguan Liu
Ashley B. Strickland
Yanli Chen
Yong Fu
Juan Xu
Mohammed Yosri
Yuchen Nan
Hong Zhou
Xiquan Zhang
Meiqing Shi
Fungal dissemination is limited by liver macrophage filtration of the blood
description Patients with liver diseases are at increased risk of fungal infections. Here the authors show that Kupffer cells are critical for the filtration of fungi out of the blood and thereby for liver-mediated protection against disseminating fungal infection.
format article
author Donglei Sun
Peng Sun
Hongmei Li
Mingshun Zhang
Gongguan Liu
Ashley B. Strickland
Yanli Chen
Yong Fu
Juan Xu
Mohammed Yosri
Yuchen Nan
Hong Zhou
Xiquan Zhang
Meiqing Shi
author_facet Donglei Sun
Peng Sun
Hongmei Li
Mingshun Zhang
Gongguan Liu
Ashley B. Strickland
Yanli Chen
Yong Fu
Juan Xu
Mohammed Yosri
Yuchen Nan
Hong Zhou
Xiquan Zhang
Meiqing Shi
author_sort Donglei Sun
title Fungal dissemination is limited by liver macrophage filtration of the blood
title_short Fungal dissemination is limited by liver macrophage filtration of the blood
title_full Fungal dissemination is limited by liver macrophage filtration of the blood
title_fullStr Fungal dissemination is limited by liver macrophage filtration of the blood
title_full_unstemmed Fungal dissemination is limited by liver macrophage filtration of the blood
title_sort fungal dissemination is limited by liver macrophage filtration of the blood
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3391e8a2cfc74237befa72af3155d7c0
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AT mingshunzhang fungaldisseminationislimitedbylivermacrophagefiltrationoftheblood
AT gongguanliu fungaldisseminationislimitedbylivermacrophagefiltrationoftheblood
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AT yuchennan fungaldisseminationislimitedbylivermacrophagefiltrationoftheblood
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