Fungal dissemination is limited by liver macrophage filtration of the blood
Patients with liver diseases are at increased risk of fungal infections. Here the authors show that Kupffer cells are critical for the filtration of fungi out of the blood and thereby for liver-mediated protection against disseminating fungal infection.
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Nature Portfolio
2019
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oai:doaj.org-article:3391e8a2cfc74237befa72af3155d7c02021-12-02T14:39:59ZFungal dissemination is limited by liver macrophage filtration of the blood10.1038/s41467-019-12381-52041-1723https://doaj.org/article/3391e8a2cfc74237befa72af3155d7c02019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12381-5https://doaj.org/toc/2041-1723Patients with liver diseases are at increased risk of fungal infections. Here the authors show that Kupffer cells are critical for the filtration of fungi out of the blood and thereby for liver-mediated protection against disseminating fungal infection.Donglei SunPeng SunHongmei LiMingshun ZhangGongguan LiuAshley B. StricklandYanli ChenYong FuJuan XuMohammed YosriYuchen NanHong ZhouXiquan ZhangMeiqing ShiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q Donglei Sun Peng Sun Hongmei Li Mingshun Zhang Gongguan Liu Ashley B. Strickland Yanli Chen Yong Fu Juan Xu Mohammed Yosri Yuchen Nan Hong Zhou Xiquan Zhang Meiqing Shi Fungal dissemination is limited by liver macrophage filtration of the blood |
description |
Patients with liver diseases are at increased risk of fungal infections. Here the authors show that Kupffer cells are critical for the filtration of fungi out of the blood and thereby for liver-mediated protection against disseminating fungal infection. |
format |
article |
author |
Donglei Sun Peng Sun Hongmei Li Mingshun Zhang Gongguan Liu Ashley B. Strickland Yanli Chen Yong Fu Juan Xu Mohammed Yosri Yuchen Nan Hong Zhou Xiquan Zhang Meiqing Shi |
author_facet |
Donglei Sun Peng Sun Hongmei Li Mingshun Zhang Gongguan Liu Ashley B. Strickland Yanli Chen Yong Fu Juan Xu Mohammed Yosri Yuchen Nan Hong Zhou Xiquan Zhang Meiqing Shi |
author_sort |
Donglei Sun |
title |
Fungal dissemination is limited by liver macrophage filtration of the blood |
title_short |
Fungal dissemination is limited by liver macrophage filtration of the blood |
title_full |
Fungal dissemination is limited by liver macrophage filtration of the blood |
title_fullStr |
Fungal dissemination is limited by liver macrophage filtration of the blood |
title_full_unstemmed |
Fungal dissemination is limited by liver macrophage filtration of the blood |
title_sort |
fungal dissemination is limited by liver macrophage filtration of the blood |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/3391e8a2cfc74237befa72af3155d7c0 |
work_keys_str_mv |
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