Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses

Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses

Noroviruses can cause gastroenteritis and there is currently no licensed vaccine or specific treatment available. Here, the authors isolate human monoclonal antibodies and characterize one antibody (NORO-320) with broad reactivity to genogroup I and II noroviruses.

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Detalles Bibliográficos
Autores principales: Gabriela Alvarado, Wilhelm Salmen, Khalil Ettayebi, Liya Hu, Banumathi Sankaran, Mary K. Estes, B. V. Venkataram Prasad, James E. Crowe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/33925668740440828a0fc9a2f93f6e1b
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Descripción
Sumario:Noroviruses can cause gastroenteritis and there is currently no licensed vaccine or specific treatment available. Here, the authors isolate human monoclonal antibodies and characterize one antibody (NORO-320) with broad reactivity to genogroup I and II noroviruses.

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