Immunotherapy in patients with non-small cell lung cancer with ECOG PS 2

Immunotherapy is a new and very pro­mising method of anti-cancer treat­ment. Unfortunately, not every patient can benefit from this treatment. The Polish drug program determines the selection of patients based on PD-L1 expression and the performance status assessed with the use of Eastern Cooperativ...

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Autores principales: Damian Mojsak, Beata Kuklińska, Michał Dębczyński, Robert Marek Mróz
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Lenguaje:EN
Publicado: Termedia Publishing House 2021
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Acceso en línea:https://doaj.org/article/33951a72defa418a95258e7273536311
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spelling oai:doaj.org-article:33951a72defa418a95258e72735363112021-12-02T17:18:57ZImmunotherapy in patients with non-small cell lung cancer with ECOG PS 21428-25261897-430910.5114/wo.2021.105031https://doaj.org/article/33951a72defa418a95258e72735363112021-04-01T00:00:00Zhttps://www.termedia.pl/Immunotherapy-in-patients-with-non-small-cell-lung-cancer-with-ECOG-PS-2,3,43720,1,1.htmlhttps://doaj.org/toc/1428-2526https://doaj.org/toc/1897-4309Immunotherapy is a new and very pro­mising method of anti-cancer treat­ment. Unfortunately, not every patient can benefit from this treatment. The Polish drug program determines the selection of patients based on PD-L1 expression and the performance status assessed with the use of Eastern Cooperative Oncology Group Perfor­mance Status (ECOG PS) score. Patients with ECOG PS 2 represent a sig­nificant proportion of the cancer population, one which is overlooked in most clinical trials of immunotherapy. Often, a reduced performance status is the only factor that excludes the patient from treatment with immunotherapy. Choosing the optimal method of treatment in patients with a worse general condition and with multiple diseases may be a significant problem for the doctor. Assessment of performance status may be a particular problem because not every patient has a worse PS score for the same reasons. In this study, we analyse the results of treatment of patients with a poorer performance status to date, and we present tools that improve the precise assessment of the degree of the performance status, which may enable more patients to access novel lung cancer treatments.Damian MojsakBeata KuklińskaMichał DębczyńskiRobert Marek MrózTermedia Publishing Housearticlenon-small cell lung cancer immunotherapy performance status.MedicineRENContemporary Oncology, Vol 25, Iss 1, Pp 53-56 (2021)
institution DOAJ
collection DOAJ
language EN
topic non-small cell lung cancer
immunotherapy
performance status.
Medicine
R
spellingShingle non-small cell lung cancer
immunotherapy
performance status.
Medicine
R
Damian Mojsak
Beata Kuklińska
Michał Dębczyński
Robert Marek Mróz
Immunotherapy in patients with non-small cell lung cancer with ECOG PS 2
description Immunotherapy is a new and very pro­mising method of anti-cancer treat­ment. Unfortunately, not every patient can benefit from this treatment. The Polish drug program determines the selection of patients based on PD-L1 expression and the performance status assessed with the use of Eastern Cooperative Oncology Group Perfor­mance Status (ECOG PS) score. Patients with ECOG PS 2 represent a sig­nificant proportion of the cancer population, one which is overlooked in most clinical trials of immunotherapy. Often, a reduced performance status is the only factor that excludes the patient from treatment with immunotherapy. Choosing the optimal method of treatment in patients with a worse general condition and with multiple diseases may be a significant problem for the doctor. Assessment of performance status may be a particular problem because not every patient has a worse PS score for the same reasons. In this study, we analyse the results of treatment of patients with a poorer performance status to date, and we present tools that improve the precise assessment of the degree of the performance status, which may enable more patients to access novel lung cancer treatments.
format article
author Damian Mojsak
Beata Kuklińska
Michał Dębczyński
Robert Marek Mróz
author_facet Damian Mojsak
Beata Kuklińska
Michał Dębczyński
Robert Marek Mróz
author_sort Damian Mojsak
title Immunotherapy in patients with non-small cell lung cancer with ECOG PS 2
title_short Immunotherapy in patients with non-small cell lung cancer with ECOG PS 2
title_full Immunotherapy in patients with non-small cell lung cancer with ECOG PS 2
title_fullStr Immunotherapy in patients with non-small cell lung cancer with ECOG PS 2
title_full_unstemmed Immunotherapy in patients with non-small cell lung cancer with ECOG PS 2
title_sort immunotherapy in patients with non-small cell lung cancer with ecog ps 2
publisher Termedia Publishing House
publishDate 2021
url https://doaj.org/article/33951a72defa418a95258e7273536311
work_keys_str_mv AT damianmojsak immunotherapyinpatientswithnonsmallcelllungcancerwithecogps2
AT beatakuklinska immunotherapyinpatientswithnonsmallcelllungcancerwithecogps2
AT michałdebczynski immunotherapyinpatientswithnonsmallcelllungcancerwithecogps2
AT robertmarekmroz immunotherapyinpatientswithnonsmallcelllungcancerwithecogps2
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