Perinatal inflammation influences but does not arrest rapid immune development in preterm babies

The infant immune system is continuously shaped by environmental factors. Here the authors demonstrate that rapid immune development in preterm babies is modulated by perinatal inflammation more than gut microbiota, and that lower CXCL8-producing T cells may identify infants susceptible to infection...

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Autores principales: S. Kamdar, R. Hutchinson, A. Laing, F. Stacey, K. Ansbro, M. R. Millar, K. Costeloe, W. G. Wade, P. Fleming, D. L. Gibbons
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/339db50187574d0b809b573991bf232a
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Sumario:The infant immune system is continuously shaped by environmental factors. Here the authors demonstrate that rapid immune development in preterm babies is modulated by perinatal inflammation more than gut microbiota, and that lower CXCL8-producing T cells may identify infants susceptible to infection.