Perinatal inflammation influences but does not arrest rapid immune development in preterm babies

The infant immune system is continuously shaped by environmental factors. Here the authors demonstrate that rapid immune development in preterm babies is modulated by perinatal inflammation more than gut microbiota, and that lower CXCL8-producing T cells may identify infants susceptible to infection...

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Autores principales:	S. Kamdar, R. Hutchinson, A. Laing, F. Stacey, K. Ansbro, M. R. Millar, K. Costeloe, W. G. Wade, P. Fleming, D. L. Gibbons
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/339db50187574d0b809b573991bf232a
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spelling	oai:doaj.org-article:339db50187574d0b809b573991bf232a2021-12-02T14:41:25ZPerinatal inflammation influences but does not arrest rapid immune development in preterm babies10.1038/s41467-020-14923-82041-1723https://doaj.org/article/339db50187574d0b809b573991bf232a2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14923-8https://doaj.org/toc/2041-1723The infant immune system is continuously shaped by environmental factors. Here the authors demonstrate that rapid immune development in preterm babies is modulated by perinatal inflammation more than gut microbiota, and that lower CXCL8-producing T cells may identify infants susceptible to infection.S. KamdarR. HutchinsonA. LaingF. StaceyK. AnsbroM. R. MillarK. CosteloeW. G. WadeP. FlemingD. L. GibbonsNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q S. Kamdar R. Hutchinson A. Laing F. Stacey K. Ansbro M. R. Millar K. Costeloe W. G. Wade P. Fleming D. L. Gibbons Perinatal inflammation influences but does not arrest rapid immune development in preterm babies
description	The infant immune system is continuously shaped by environmental factors. Here the authors demonstrate that rapid immune development in preterm babies is modulated by perinatal inflammation more than gut microbiota, and that lower CXCL8-producing T cells may identify infants susceptible to infection.
format	article
author	S. Kamdar R. Hutchinson A. Laing F. Stacey K. Ansbro M. R. Millar K. Costeloe W. G. Wade P. Fleming D. L. Gibbons
author_facet	S. Kamdar R. Hutchinson A. Laing F. Stacey K. Ansbro M. R. Millar K. Costeloe W. G. Wade P. Fleming D. L. Gibbons
author_sort	S. Kamdar
title	Perinatal inflammation influences but does not arrest rapid immune development in preterm babies
title_short	Perinatal inflammation influences but does not arrest rapid immune development in preterm babies
title_full	Perinatal inflammation influences but does not arrest rapid immune development in preterm babies
title_fullStr	Perinatal inflammation influences but does not arrest rapid immune development in preterm babies
title_full_unstemmed	Perinatal inflammation influences but does not arrest rapid immune development in preterm babies
title_sort	perinatal inflammation influences but does not arrest rapid immune development in preterm babies
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/339db50187574d0b809b573991bf232a
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Perinatal inflammation influences but does not arrest rapid immune development in preterm babies

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