Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study

Abstract Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We catego...

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Autores principales:	Dae-Yeon Lee, Min-Gyu Yoo, Hyo-Jin Kim, Han Byul Jang, Jae-Hong Kim, Hye-Ja Lee, Sang Ick Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/33a3dc0446964fe59a6bde1fe653b956
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spelling	oai:doaj.org-article:33a3dc0446964fe59a6bde1fe653b9562021-12-02T11:52:18ZAssociation between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study10.1038/s41598-017-07549-22045-2322https://doaj.org/article/33a3dc0446964fe59a6bde1fe653b9562017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07549-2https://doaj.org/toc/2045-2322Abstract Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into four groups—based on the baseline (one-point measure; non-drinking, <5 g/day, ≥5, <30 g/day, and ≥30 g/day) and follow-up (consumption pattern; never-drinking, light, moderate, and heavy drinking) measurement. At baseline, ≥30 g/day alcohol consumption increased the risk of incident diabetes (HR: 1.42; 95% CI, 1.10–1.85), but ≥5, <30 g/day alcohol consumption had no effects on the incident diabetes. Meanwhile, when using the alcohol consumption pattern, a heavy-drinking pattern increased the risk of incident diabetes (HR = 1.32, 1.01–1.73), but the light and moderate consumption pattern was associated with a reduced risk of type 2 diabetes (HR: 0.66; 0.50–0.87 and HR: 0.74; 0.57–0.95, respectively). At the end point of follow-up, the insulinogenic index (IGI), but not the insulin sensitivity index (ISI), differed among the groups. Alcohol consumption pattern had a J-shaped association with the incident type 2 diabetes in Korean men. The IGI showed an inverted J-shaped association according to alcohol drinking pattern, but the ISI was not a J-shape.Dae-Yeon LeeMin-Gyu YooHyo-Jin KimHan Byul JangJae-Hong KimHye-Ja LeeSang Ick ParkNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dae-Yeon Lee Min-Gyu Yoo Hyo-Jin Kim Han Byul Jang Jae-Hong Kim Hye-Ja Lee Sang Ick Park Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study
description	Abstract Moderate alcohol consumption is generally associated with reduced risk of type 2 diabetes. However, this beneficial effects of alcohol intake remains controversial due to inconsistent results across studies. The analysis was performed using data from the Ansung-Ansan cohort study. We categorized the participants into four groups—based on the baseline (one-point measure; non-drinking, <5 g/day, ≥5, <30 g/day, and ≥30 g/day) and follow-up (consumption pattern; never-drinking, light, moderate, and heavy drinking) measurement. At baseline, ≥30 g/day alcohol consumption increased the risk of incident diabetes (HR: 1.42; 95% CI, 1.10–1.85), but ≥5, <30 g/day alcohol consumption had no effects on the incident diabetes. Meanwhile, when using the alcohol consumption pattern, a heavy-drinking pattern increased the risk of incident diabetes (HR = 1.32, 1.01–1.73), but the light and moderate consumption pattern was associated with a reduced risk of type 2 diabetes (HR: 0.66; 0.50–0.87 and HR: 0.74; 0.57–0.95, respectively). At the end point of follow-up, the insulinogenic index (IGI), but not the insulin sensitivity index (ISI), differed among the groups. Alcohol consumption pattern had a J-shaped association with the incident type 2 diabetes in Korean men. The IGI showed an inverted J-shaped association according to alcohol drinking pattern, but the ISI was not a J-shape.
format	article
author	Dae-Yeon Lee Min-Gyu Yoo Hyo-Jin Kim Han Byul Jang Jae-Hong Kim Hye-Ja Lee Sang Ick Park
author_facet	Dae-Yeon Lee Min-Gyu Yoo Hyo-Jin Kim Han Byul Jang Jae-Hong Kim Hye-Ja Lee Sang Ick Park
author_sort	Dae-Yeon Lee
title	Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study
title_short	Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study
title_full	Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study
title_fullStr	Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study
title_full_unstemmed	Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study
title_sort	association between alcohol consumption pattern and the incidence risk of type 2 diabetes in korean men: a 12-years follow-up study
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/33a3dc0446964fe59a6bde1fe653b956
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Association between alcohol consumption pattern and the incidence risk of type 2 diabetes in Korean men: A 12-years follow-up study

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