Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line

Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line

Complex traits associate with genetic variation and environment and their interaction. Here, the authors study the influence of different diets on trait variability in 1154 outbred mice from an advanced intercross line and find gene-diet interactions associated with spontaneous autoimmunity developm...

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Autores principales: Artem Vorobyev, Yask Gupta, Tanya Sezin, Hiroshi Koga, Yannic C. Bartsch, Meriem Belheouane, Sven Künzel, Christian Sina, Paul Schilf, Heiko Körber-Ahrens, Foteini Beltsiou, Anna Lara Ernst, Stanislav Khil’chenko, Hassanin Al-Aasam, Rudolf A. Manz, Sandra Diehl, Moritz Steinhaus, Joanna Jascholt, Phillip Kouki, Wolf-Henning Boehncke, Tanya N. Mayadas, Detlef Zillikens, Christian D. Sadik, Hiroshi Nishi, Marc Ehlers, Steffen Möller, Katja Bieber, John F. Baines, Saleh M. Ibrahim, Ralf J. Ludwig
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/33aa09018c92411598dc61043de133d0
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spelling oai:doaj.org-article:33aa09018c92411598dc61043de133d02021-12-02T14:38:40ZGene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line10.1038/s41467-019-11952-w2041-1723https://doaj.org/article/33aa09018c92411598dc61043de133d02019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11952-whttps://doaj.org/toc/2041-1723Complex traits associate with genetic variation and environment and their interaction. Here, the authors study the influence of different diets on trait variability in 1154 outbred mice from an advanced intercross line and find gene-diet interactions associated with spontaneous autoimmunity development in these animals.Artem VorobyevYask GuptaTanya SezinHiroshi KogaYannic C. BartschMeriem BelheouaneSven KünzelChristian SinaPaul SchilfHeiko Körber-AhrensFoteini BeltsiouAnna Lara ErnstStanislav Khil’chenkoHassanin Al-AasamRudolf A. ManzSandra DiehlMoritz SteinhausJoanna JascholtPhillip KoukiWolf-Henning BoehnckeTanya N. MayadasDetlef ZillikensChristian D. SadikHiroshi NishiMarc EhlersSteffen MöllerKatja BieberJohn F. BainesSaleh M. IbrahimRalf J. LudwigNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Artem Vorobyev
Yask Gupta
Tanya Sezin
Hiroshi Koga
Yannic C. Bartsch
Meriem Belheouane
Sven Künzel
Christian Sina
Paul Schilf
Heiko Körber-Ahrens
Foteini Beltsiou
Anna Lara Ernst
Stanislav Khil’chenko
Hassanin Al-Aasam
Rudolf A. Manz
Sandra Diehl
Moritz Steinhaus
Joanna Jascholt
Phillip Kouki
Wolf-Henning Boehncke
Tanya N. Mayadas
Detlef Zillikens
Christian D. Sadik
Hiroshi Nishi
Marc Ehlers
Steffen Möller
Katja Bieber
John F. Baines
Saleh M. Ibrahim
Ralf J. Ludwig
Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
description Complex traits associate with genetic variation and environment and their interaction. Here, the authors study the influence of different diets on trait variability in 1154 outbred mice from an advanced intercross line and find gene-diet interactions associated with spontaneous autoimmunity development in these animals.
format article
author Artem Vorobyev
Yask Gupta
Tanya Sezin
Hiroshi Koga
Yannic C. Bartsch
Meriem Belheouane
Sven Künzel
Christian Sina
Paul Schilf
Heiko Körber-Ahrens
Foteini Beltsiou
Anna Lara Ernst
Stanislav Khil’chenko
Hassanin Al-Aasam
Rudolf A. Manz
Sandra Diehl
Moritz Steinhaus
Joanna Jascholt
Phillip Kouki
Wolf-Henning Boehncke
Tanya N. Mayadas
Detlef Zillikens
Christian D. Sadik
Hiroshi Nishi
Marc Ehlers
Steffen Möller
Katja Bieber
John F. Baines
Saleh M. Ibrahim
Ralf J. Ludwig
author_facet Artem Vorobyev
Yask Gupta
Tanya Sezin
Hiroshi Koga
Yannic C. Bartsch
Meriem Belheouane
Sven Künzel
Christian Sina
Paul Schilf
Heiko Körber-Ahrens
Foteini Beltsiou
Anna Lara Ernst
Stanislav Khil’chenko
Hassanin Al-Aasam
Rudolf A. Manz
Sandra Diehl
Moritz Steinhaus
Joanna Jascholt
Phillip Kouki
Wolf-Henning Boehncke
Tanya N. Mayadas
Detlef Zillikens
Christian D. Sadik
Hiroshi Nishi
Marc Ehlers
Steffen Möller
Katja Bieber
John F. Baines
Saleh M. Ibrahim
Ralf J. Ludwig
author_sort Artem Vorobyev
title Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
title_short Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
title_full Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
title_fullStr Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
title_full_unstemmed Gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
title_sort gene-diet interactions associated with complex trait variation in an advanced intercross outbred mouse line
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/33aa09018c92411598dc61043de133d0
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