Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation

Thyroid cancer is very rare in children and papillary thyroid carcinoma (PTC) represents the most common type. Patients are frequently in the second decade of life and complain of painless enlargement of the gland. Pediatric PTC has unique clinicopathologic characteristics that make it different fro...

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Autores principales:	Tariq N Aladily, Majd Khader, Nadwa Bustami, Osama A Samara
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
Materias:	lymphoma papillary thyroid carcinoma pediatric cancer thyroid carcinoma tuberculosis Medicine R
Acceso en línea:	https://doaj.org/article/33ad77c2c2294dfca49b859c6ba7ac33
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spelling	oai:doaj.org-article:33ad77c2c2294dfca49b859c6ba7ac332021-12-02T19:02:51ZPapillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation2231-07702249-446410.4103/ajm.ajm_288_20https://doaj.org/article/33ad77c2c2294dfca49b859c6ba7ac332021-04-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.ajm_288_20https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Thyroid cancer is very rare in children and papillary thyroid carcinoma (PTC) represents the most common type. Patients are frequently in the second decade of life and complain of painless enlargement of the gland. Pediatric PTC has unique clinicopathologic characteristics that make it different from the adult counterpart. The biologic behavior tends to be aggressive and patients frequently present with advanced disease. Herein, we report a case with an unusual presentation. A 5-year-old child manifested with fever, night sweats, cervical lymphadenopathy, and weight loss for 2 months. He also complained of mild cough and shortness of breath. Clinical suspicion of tuberculosis or lymphoma was raised, but laboratory workup was unremarkable. Cervical lymph node excision was done, and the histopathologic examination showed metastatic PTC. The patient underwent surgical and radioactive therapy and remained in complete remission for 5 years. Unfortunately, the disease ultimately relapsed with disseminated metastasis and the patient passed away.Tariq N AladilyMajd KhaderNadwa BustamiOsama A SamaraThieme Medical and Scientific Publishers Pvt. Ltd.articlelymphomapapillary thyroid carcinomapediatric cancerthyroid carcinomatuberculosisMedicineRENAvicenna Journal of Medicine, Vol 11, Iss 02, Pp 103-106 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	lymphoma papillary thyroid carcinoma pediatric cancer thyroid carcinoma tuberculosis Medicine R
spellingShingle	lymphoma papillary thyroid carcinoma pediatric cancer thyroid carcinoma tuberculosis Medicine R Tariq N Aladily Majd Khader Nadwa Bustami Osama A Samara Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation
description	Thyroid cancer is very rare in children and papillary thyroid carcinoma (PTC) represents the most common type. Patients are frequently in the second decade of life and complain of painless enlargement of the gland. Pediatric PTC has unique clinicopathologic characteristics that make it different from the adult counterpart. The biologic behavior tends to be aggressive and patients frequently present with advanced disease. Herein, we report a case with an unusual presentation. A 5-year-old child manifested with fever, night sweats, cervical lymphadenopathy, and weight loss for 2 months. He also complained of mild cough and shortness of breath. Clinical suspicion of tuberculosis or lymphoma was raised, but laboratory workup was unremarkable. Cervical lymph node excision was done, and the histopathologic examination showed metastatic PTC. The patient underwent surgical and radioactive therapy and remained in complete remission for 5 years. Unfortunately, the disease ultimately relapsed with disseminated metastasis and the patient passed away.
format	article
author	Tariq N Aladily Majd Khader Nadwa Bustami Osama A Samara
author_facet	Tariq N Aladily Majd Khader Nadwa Bustami Osama A Samara
author_sort	Tariq N Aladily
title	Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation
title_short	Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation
title_full	Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation
title_fullStr	Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation
title_full_unstemmed	Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation
title_sort	papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2021
url	https://doaj.org/article/33ad77c2c2294dfca49b859c6ba7ac33
work_keys_str_mv	AT tariqnaladily papillarythyroidcarcinomaina5yearoldchildmimickinglymphomainpresentation AT majdkhader papillarythyroidcarcinomaina5yearoldchildmimickinglymphomainpresentation AT nadwabustami papillarythyroidcarcinomaina5yearoldchildmimickinglymphomainpresentation AT osamaasamara papillarythyroidcarcinomaina5yearoldchildmimickinglymphomainpresentation
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Papillary thyroid carcinoma in a 5-year old child, mimicking lymphoma in presentation

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