Genome-wide assessment of differential translations with ribosome profiling data

The global measurement of ribosome occupancy on mRNAs is commonly used as a proxy in estimating rates of protein synthesis. Here the authors describe Xtail, a computational approach that facilitates the extraction of accurate quantitative insight from ribosome profiling data (Ribo-Seq).

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Autores principales: Zhengtao Xiao, Qin Zou, Yu Liu, Xuerui Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/33b162b5cdac4362be0f06655687ec88
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spelling oai:doaj.org-article:33b162b5cdac4362be0f06655687ec882021-12-02T17:33:22ZGenome-wide assessment of differential translations with ribosome profiling data10.1038/ncomms111942041-1723https://doaj.org/article/33b162b5cdac4362be0f06655687ec882016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11194https://doaj.org/toc/2041-1723The global measurement of ribosome occupancy on mRNAs is commonly used as a proxy in estimating rates of protein synthesis. Here the authors describe Xtail, a computational approach that facilitates the extraction of accurate quantitative insight from ribosome profiling data (Ribo-Seq).Zhengtao XiaoQin ZouYu LiuXuerui YangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhengtao Xiao
Qin Zou
Yu Liu
Xuerui Yang
Genome-wide assessment of differential translations with ribosome profiling data
description The global measurement of ribosome occupancy on mRNAs is commonly used as a proxy in estimating rates of protein synthesis. Here the authors describe Xtail, a computational approach that facilitates the extraction of accurate quantitative insight from ribosome profiling data (Ribo-Seq).
format article
author Zhengtao Xiao
Qin Zou
Yu Liu
Xuerui Yang
author_facet Zhengtao Xiao
Qin Zou
Yu Liu
Xuerui Yang
author_sort Zhengtao Xiao
title Genome-wide assessment of differential translations with ribosome profiling data
title_short Genome-wide assessment of differential translations with ribosome profiling data
title_full Genome-wide assessment of differential translations with ribosome profiling data
title_fullStr Genome-wide assessment of differential translations with ribosome profiling data
title_full_unstemmed Genome-wide assessment of differential translations with ribosome profiling data
title_sort genome-wide assessment of differential translations with ribosome profiling data
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/33b162b5cdac4362be0f06655687ec88
work_keys_str_mv AT zhengtaoxiao genomewideassessmentofdifferentialtranslationswithribosomeprofilingdata
AT qinzou genomewideassessmentofdifferentialtranslationswithribosomeprofilingdata
AT yuliu genomewideassessmentofdifferentialtranslationswithribosomeprofilingdata
AT xueruiyang genomewideassessmentofdifferentialtranslationswithribosomeprofilingdata
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