Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study

Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study

Abstract This study evaluates the impact of breast cancer (BC) in health related quality of life (HRQL) and in psychological distress (PD) during the initial phases of the disease and looks for contributing factors. A multicentric case-control study, EpiGEICAM, was carried out. Incident BC cases and...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Nerea Fernández de Larrea-Baz, Beatriz Pérez-Gómez, Ángel Guerrero-Zotano, Ana María Casas, Begoña Bermejo, José Manuel Baena-Cañada, Silvia Antolin, Pedro Sánchez-Rovira, Manuel Ramos Vázquez, José Ángel Garcia-Sáenz, Antonio Antón, Montserrat Muñoz, Ana de Juan, Carlos Jara, José Ignacio Chacón, Angels Arcusa, Miguel Gil-Gil, Encarna Adrover, Amparo Oltra, Joan Brunet, Sonia González, Susana Bezares, Virginia Lope, Miguel Martín, Marina Pollán
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/33b3d22231de42aba2eaca043fcc939b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Abstract This study evaluates the impact of breast cancer (BC) in health related quality of life (HRQL) and in psychological distress (PD) during the initial phases of the disease and looks for contributing factors. A multicentric case-control study, EpiGEICAM, was carried out. Incident BC cases and age- and residence- matched controls were included. Clinical, epidemiological, HRQL (SF-36) and PD information (GHQ-28) was collected. We used multivariable logistic regression models to estimate OR of low HRQL and of PD in cases compared to controls, and to identify factors associated with low HRQL and with PD. Among 896 BC cases and 890 control women, cases had poorer scores than both, the reference population and the control group, in all SF-36 scales. BC women with lower education, younger, active workers, never smokers, those with comorbidities, in stage IV and with surgical treatment had lower physical HRQL; factors associated with low mental HRQL were dissatisfaction with social support, being current smoker and having children. Cases had a fivefold increased odds of PD compared to controls. Managing comorbidities and trying to promote social support, especially in younger and less educated women, could improve well-being of BC patients.

Ejemplares similares