Optogenetic restoration of retinal ganglion cell activity in the living primate

Non-human primate models are important for the development of high quality vision restoration therapies for blindness. Here, the authors demonstrate restoration of light responses in foveal retinal ganglion cells of the living macaque following optogenetic gene therapy.

Guardado en:

Detalles Bibliográficos
Autores principales:	Juliette E. McGregor, Tyler Godat, Kamal R. Dhakal, Keith Parkins, Jennifer M. Strazzeri, Brittany A. Bateman, William S. Fischer, David R. Williams, William H. Merigan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/33b6fdff1a8e45128d99265011a8ee2c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:33b6fdff1a8e45128d99265011a8ee2c
record_format	dspace
spelling	oai:doaj.org-article:33b6fdff1a8e45128d99265011a8ee2c2021-12-02T15:37:07ZOptogenetic restoration of retinal ganglion cell activity in the living primate10.1038/s41467-020-15317-62041-1723https://doaj.org/article/33b6fdff1a8e45128d99265011a8ee2c2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15317-6https://doaj.org/toc/2041-1723Non-human primate models are important for the development of high quality vision restoration therapies for blindness. Here, the authors demonstrate restoration of light responses in foveal retinal ganglion cells of the living macaque following optogenetic gene therapy.Juliette E. McGregorTyler GodatKamal R. DhakalKeith ParkinsJennifer M. StrazzeriBrittany A. BatemanWilliam S. FischerDavid R. WilliamsWilliam H. MeriganNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Juliette E. McGregor Tyler Godat Kamal R. Dhakal Keith Parkins Jennifer M. Strazzeri Brittany A. Bateman William S. Fischer David R. Williams William H. Merigan Optogenetic restoration of retinal ganglion cell activity in the living primate
description	Non-human primate models are important for the development of high quality vision restoration therapies for blindness. Here, the authors demonstrate restoration of light responses in foveal retinal ganglion cells of the living macaque following optogenetic gene therapy.
format	article
author	Juliette E. McGregor Tyler Godat Kamal R. Dhakal Keith Parkins Jennifer M. Strazzeri Brittany A. Bateman William S. Fischer David R. Williams William H. Merigan
author_facet	Juliette E. McGregor Tyler Godat Kamal R. Dhakal Keith Parkins Jennifer M. Strazzeri Brittany A. Bateman William S. Fischer David R. Williams William H. Merigan
author_sort	Juliette E. McGregor
title	Optogenetic restoration of retinal ganglion cell activity in the living primate
title_short	Optogenetic restoration of retinal ganglion cell activity in the living primate
title_full	Optogenetic restoration of retinal ganglion cell activity in the living primate
title_fullStr	Optogenetic restoration of retinal ganglion cell activity in the living primate
title_full_unstemmed	Optogenetic restoration of retinal ganglion cell activity in the living primate
title_sort	optogenetic restoration of retinal ganglion cell activity in the living primate
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/33b6fdff1a8e45128d99265011a8ee2c
work_keys_str_mv	AT julietteemcgregor optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT tylergodat optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT kamalrdhakal optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT keithparkins optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT jennifermstrazzeri optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT brittanyabateman optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT williamsfischer optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT davidrwilliams optogeneticrestorationofretinalganglioncellactivityinthelivingprimate AT williamhmerigan optogeneticrestorationofretinalganglioncellactivityinthelivingprimate
_version_	1718386223701032960

Optogenetic restoration of retinal ganglion cell activity in the living primate

Ejemplares similares