Replication landscape of the human genome

The physical origin and termination sites of DNA replication in human cells have remained elusive. Here the authors use Okazaki fragment sequencing to reveal global replication patterns and show how chromatin and transcription modulate the process.

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Autores principales:	Nataliya Petryk, Malik Kahli, Yves d'Aubenton-Carafa, Yan Jaszczyszyn, Yimin Shen, Maud Silvain, Claude Thermes, Chun-Long Chen, Olivier Hyrien
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/33be268cd5f4463da7c86414495060a0
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id	oai:doaj.org-article:33be268cd5f4463da7c86414495060a0
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spelling	oai:doaj.org-article:33be268cd5f4463da7c86414495060a02021-12-02T16:49:58ZReplication landscape of the human genome10.1038/ncomms102082041-1723https://doaj.org/article/33be268cd5f4463da7c86414495060a02016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10208https://doaj.org/toc/2041-1723The physical origin and termination sites of DNA replication in human cells have remained elusive. Here the authors use Okazaki fragment sequencing to reveal global replication patterns and show how chromatin and transcription modulate the process.Nataliya PetrykMalik KahliYves d'Aubenton-CarafaYan JaszczyszynYimin ShenMaud SilvainClaude ThermesChun-Long ChenOlivier HyrienNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nataliya Petryk Malik Kahli Yves d'Aubenton-Carafa Yan Jaszczyszyn Yimin Shen Maud Silvain Claude Thermes Chun-Long Chen Olivier Hyrien Replication landscape of the human genome
description	The physical origin and termination sites of DNA replication in human cells have remained elusive. Here the authors use Okazaki fragment sequencing to reveal global replication patterns and show how chromatin and transcription modulate the process.
format	article
author	Nataliya Petryk Malik Kahli Yves d'Aubenton-Carafa Yan Jaszczyszyn Yimin Shen Maud Silvain Claude Thermes Chun-Long Chen Olivier Hyrien
author_facet	Nataliya Petryk Malik Kahli Yves d'Aubenton-Carafa Yan Jaszczyszyn Yimin Shen Maud Silvain Claude Thermes Chun-Long Chen Olivier Hyrien
author_sort	Nataliya Petryk
title	Replication landscape of the human genome
title_short	Replication landscape of the human genome
title_full	Replication landscape of the human genome
title_fullStr	Replication landscape of the human genome
title_full_unstemmed	Replication landscape of the human genome
title_sort	replication landscape of the human genome
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/33be268cd5f4463da7c86414495060a0
work_keys_str_mv	AT nataliyapetryk replicationlandscapeofthehumangenome AT malikkahli replicationlandscapeofthehumangenome AT yvesdaubentoncarafa replicationlandscapeofthehumangenome AT yanjaszczyszyn replicationlandscapeofthehumangenome AT yiminshen replicationlandscapeofthehumangenome AT maudsilvain replicationlandscapeofthehumangenome AT claudethermes replicationlandscapeofthehumangenome AT chunlongchen replicationlandscapeofthehumangenome AT olivierhyrien replicationlandscapeofthehumangenome
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Replication landscape of the human genome

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