Design of synthetic human gut microbiome assembly and butyrate production

Microbiomes designed with predictable functions could enable broad applications in health, agriculture and bioprocessing. Here the authors use a model-guided approach to design diverse synthetic human gut communities for production of the health-relevant metabolite butyrate.

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Detalles Bibliográficos
Autores principales:	Ryan L. Clark, Bryce M. Connors, David M. Stevenson, Susan E. Hromada, Joshua J. Hamilton, Daniel Amador-Noguez, Ophelia S. Venturelli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/33d2cdec301546449e914c3a28be1c76
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spelling	oai:doaj.org-article:33d2cdec301546449e914c3a28be1c762021-12-02T15:02:29ZDesign of synthetic human gut microbiome assembly and butyrate production10.1038/s41467-021-22938-y2041-1723https://doaj.org/article/33d2cdec301546449e914c3a28be1c762021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22938-yhttps://doaj.org/toc/2041-1723Microbiomes designed with predictable functions could enable broad applications in health, agriculture and bioprocessing. Here the authors use a model-guided approach to design diverse synthetic human gut communities for production of the health-relevant metabolite butyrate.Ryan L. ClarkBryce M. ConnorsDavid M. StevensonSusan E. HromadaJoshua J. HamiltonDaniel Amador-NoguezOphelia S. VenturelliNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ryan L. Clark Bryce M. Connors David M. Stevenson Susan E. Hromada Joshua J. Hamilton Daniel Amador-Noguez Ophelia S. Venturelli Design of synthetic human gut microbiome assembly and butyrate production
description	Microbiomes designed with predictable functions could enable broad applications in health, agriculture and bioprocessing. Here the authors use a model-guided approach to design diverse synthetic human gut communities for production of the health-relevant metabolite butyrate.
format	article
author	Ryan L. Clark Bryce M. Connors David M. Stevenson Susan E. Hromada Joshua J. Hamilton Daniel Amador-Noguez Ophelia S. Venturelli
author_facet	Ryan L. Clark Bryce M. Connors David M. Stevenson Susan E. Hromada Joshua J. Hamilton Daniel Amador-Noguez Ophelia S. Venturelli
author_sort	Ryan L. Clark
title	Design of synthetic human gut microbiome assembly and butyrate production
title_short	Design of synthetic human gut microbiome assembly and butyrate production
title_full	Design of synthetic human gut microbiome assembly and butyrate production
title_fullStr	Design of synthetic human gut microbiome assembly and butyrate production
title_full_unstemmed	Design of synthetic human gut microbiome assembly and butyrate production
title_sort	design of synthetic human gut microbiome assembly and butyrate production
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/33d2cdec301546449e914c3a28be1c76
work_keys_str_mv	AT ryanlclark designofsynthetichumangutmicrobiomeassemblyandbutyrateproduction AT brycemconnors designofsynthetichumangutmicrobiomeassemblyandbutyrateproduction AT davidmstevenson designofsynthetichumangutmicrobiomeassemblyandbutyrateproduction AT susanehromada designofsynthetichumangutmicrobiomeassemblyandbutyrateproduction AT joshuajhamilton designofsynthetichumangutmicrobiomeassemblyandbutyrateproduction AT danielamadornoguez designofsynthetichumangutmicrobiomeassemblyandbutyrateproduction AT opheliasventurelli designofsynthetichumangutmicrobiomeassemblyandbutyrateproduction
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Design of synthetic human gut microbiome assembly and butyrate production

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