Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin
Abstract Most patients with hepatocellular carcinoma (HCC) are in the middle or advanced stage at the time of diagnosis, and the therapeutic effect is limited. Therefore, this study aimed to verify whether deoxythymidylate kinase (DTYMK) increased in HCC and was an effective therapeutic target in HC...
Enregistré dans:
Auteurs principaux: | Fengze Sun, Yuanyuan Liu, Tingting Gong, Qiuzhong Pan, Tong Xiang, Jingjing Zhao, Yan Tang, Hao Chen, Yulong Han, Mengjia Song, Yue Huang, Han Li, Yuanyuan Chen, Chaopin Yang, Jieying Yang, Qijing Wang, Yongqiang Li, Jia He, Desheng Weng, Ruiqing Peng, Jianchuan Xia |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Publishing Group
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/33d3a7e398e24d5bbbe7ee462a878d6f |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
par: Na Sun, et autres
Publié: (2020) -
Predicting effects on oxaliplatin clearance: in vitro, kinetic and clinical studies of calcium- and magnesium-mediated oxaliplatin degradation
par: Catherine H. Han, et autres
Publié: (2017) -
Elevated Serum Uric Acid is Associated With Poor Survival in Advanced HCC Patients and Febuxostat Improves Prognosis in HCC Rats
par: Le Wu, et autres
Publié: (2021) -
Molecular Signature and Immune Landscape of HCV-Associated Hepatocellular Carcinoma (HCC): Differences and Similarities with HBV-HCC
par: De Battista D, et autres
Publié: (2021) -
Targeting T Cell Subtypes for NAFLD and NAFLD-Related HCC Treatment: An Opinion
par: Chunye Zhang, et autres
Publié: (2021)