In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

Raman spectroscopic imaging (RSI) can provide information on the chemical composition of a sample, but application to living organisms has lacked sufficient spatial resolution and signal strength. Here the authors apply confocal RSI to whole-mount zebrafish embryos to distinguish different infectiou...

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Autores principales:	Håkon Høgset, Conor C. Horgan, James P. K. Armstrong, Mads S. Bergholt, Vincenzo Torraca, Qu Chen, Timothy J. Keane, Laurence Bugeon, Margaret J. Dallman, Serge Mostowy, Molly M. Stevens
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/33d53c0ca7dc46f4a43e583729072cb2
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spelling	oai:doaj.org-article:33d53c0ca7dc46f4a43e583729072cb22021-12-02T15:37:15ZIn vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy10.1038/s41467-020-19827-12041-1723https://doaj.org/article/33d53c0ca7dc46f4a43e583729072cb22020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19827-1https://doaj.org/toc/2041-1723Raman spectroscopic imaging (RSI) can provide information on the chemical composition of a sample, but application to living organisms has lacked sufficient spatial resolution and signal strength. Here the authors apply confocal RSI to whole-mount zebrafish embryos to distinguish different infectious bacteria and to living zebrafish embryos to monitor the wound healing process.Håkon HøgsetConor C. HorganJames P. K. ArmstrongMads S. BergholtVincenzo TorracaQu ChenTimothy J. KeaneLaurence BugeonMargaret J. DallmanSerge MostowyMolly M. StevensNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Håkon Høgset Conor C. Horgan James P. K. Armstrong Mads S. Bergholt Vincenzo Torraca Qu Chen Timothy J. Keane Laurence Bugeon Margaret J. Dallman Serge Mostowy Molly M. Stevens In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
description	Raman spectroscopic imaging (RSI) can provide information on the chemical composition of a sample, but application to living organisms has lacked sufficient spatial resolution and signal strength. Here the authors apply confocal RSI to whole-mount zebrafish embryos to distinguish different infectious bacteria and to living zebrafish embryos to monitor the wound healing process.
format	article
author	Håkon Høgset Conor C. Horgan James P. K. Armstrong Mads S. Bergholt Vincenzo Torraca Qu Chen Timothy J. Keane Laurence Bugeon Margaret J. Dallman Serge Mostowy Molly M. Stevens
author_facet	Håkon Høgset Conor C. Horgan James P. K. Armstrong Mads S. Bergholt Vincenzo Torraca Qu Chen Timothy J. Keane Laurence Bugeon Margaret J. Dallman Serge Mostowy Molly M. Stevens
author_sort	Håkon Høgset
title	In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
title_short	In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
title_full	In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
title_fullStr	In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
title_full_unstemmed	In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
title_sort	in vivo biomolecular imaging of zebrafish embryos using confocal raman spectroscopy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/33d53c0ca7dc46f4a43e583729072cb2
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In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy

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