The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove

The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove

Toxicological effects of 25H-NBOMe and 25H-NBOH recreational drugs on zebrafish embryos and larvae at the end of 96 h exposure period were demonstrated. 25H-NBOH and 25H-NBOMe caused high embryo mortality at 80 and 100 µg mL−1, respectively. According to the decrease in the concentration tested, let...

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Bibliographic Details
Main Authors: Wellington Alves de Barros, Camila da Silva Nunes, Juliana Alves da Costa Ribeiro Souza, Igor José dos Santos Nascimento, Isis Martins Figueiredo, Thiago Mendonça de Aquino, Leonardo Vieira, Davi Farias, Josué Carinhanha Caldas Santos, Ângelo de Fátima
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Phenethylamines
Recreational drugs
DNA interaction
Malformation
Embryo mortality
Toxicology. Poisons
RA1190-1270
Online Access:https://doaj.org/article/33d8723e2d5e4a208fac2691c0f4621d
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