Common mtDNA variations at C5178a and A249d/T6392C/G10310A decrease the risk of severe COVID-19 in a Han Chinese population from Central China

Common mtDNA variations at C5178a and A249d/T6392C/G10310A decrease the risk of severe COVID-19 in a Han Chinese population from Central China

Abstract Background Mitochondria have been shown to play vital roles during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) development. Currently, it is unclear whether mitochondrial DNA (mtDNA) variants, which define mtDNA haplogroups...

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Bibliographic Details
Main Authors: Yi Wu, Xian-Hui Wang, Xi-Hua Li, Li-Yuan Song, Shi-Long Yu, Zhi-Cheng Fang, Yu-Quan Liu, Le-Yong Yuan, Chun-Yan Peng, Shen-Yi Zhang, Wang Cheng, Hong-Chao Ma, Li-Feng Wang, Jun-Ming Tang, Yun-Fu Wang, Fu-Yun Ji
Format: article
Language:EN
Published: BMC 2021
Subjects:
MtDNA variations
SARS-CoV-2
COVID-19
Risk
Han Chinese
Medicine (General)
R5-920
Military Science
U
Online Access:https://doaj.org/article/33d8fccb16bf4eedaff444b853677db1
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