ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
Perivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter o...
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oai:doaj.org-article:33f6650dffd545e9b3251fe59ba4493a2021-11-18T08:03:48ZROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES1563-06252313-741X10.15789/1563-0625-2019-4-633-642https://doaj.org/article/33f6650dffd545e9b3251fe59ba4493a2019-10-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1607https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XPerivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter of the vessels. Adipocytokines and chemokines, secreted from the perivascular adipose tissue, apparently have direct access to the adjacent arterial wall by diffusion, or through vasa vasorum. The present data indicate that perivascular adipose tissue plays an important role in atherosclerosis, hypertension. Recently, some studies were performed that examined the role of perivascular adipose tissue in non-atherosclerotic vascular diseases, such as neointimal formation, aortic aneurysm, arterial stiffness and vasculitis. The present review will discuss a role of perivascular adipose tissue in pathogenesis of atherosclerosis, hypertension and non-atherosclerotic vascular diseases.E. G. UchasovaO V GruzdevaYu A DylevaE V BelikSPb RAACIarticleperivascular adipose tissueadipokinescytokinesatherosclerosishypertensioncardiovascular diseasesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 21, Iss 4, Pp 633-642 (2019) |
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DOAJ |
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RU |
topic |
perivascular adipose tissue adipokines cytokines atherosclerosis hypertension cardiovascular diseases Immunologic diseases. Allergy RC581-607 |
spellingShingle |
perivascular adipose tissue adipokines cytokines atherosclerosis hypertension cardiovascular diseases Immunologic diseases. Allergy RC581-607 E. G. Uchasova O V Gruzdeva Yu A Dyleva E V Belik ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
description |
Perivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter of the vessels. Adipocytokines and chemokines, secreted from the perivascular adipose tissue, apparently have direct access to the adjacent arterial wall by diffusion, or through vasa vasorum. The present data indicate that perivascular adipose tissue plays an important role in atherosclerosis, hypertension. Recently, some studies were performed that examined the role of perivascular adipose tissue in non-atherosclerotic vascular diseases, such as neointimal formation, aortic aneurysm, arterial stiffness and vasculitis. The present review will discuss a role of perivascular adipose tissue in pathogenesis of atherosclerosis, hypertension and non-atherosclerotic vascular diseases. |
format |
article |
author |
E. G. Uchasova O V Gruzdeva Yu A Dyleva E V Belik |
author_facet |
E. G. Uchasova O V Gruzdeva Yu A Dyleva E V Belik |
author_sort |
E. G. Uchasova |
title |
ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
title_short |
ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
title_full |
ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
title_fullStr |
ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
title_full_unstemmed |
ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
title_sort |
role of perivascular adipose tissue in the development of atherosclerotic and nonatherosclerotic diseases |
publisher |
SPb RAACI |
publishDate |
2019 |
url |
https://doaj.org/article/33f6650dffd545e9b3251fe59ba4493a |
work_keys_str_mv |
AT eguchasova roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases AT ovgruzdeva roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases AT yuadyleva roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases AT evbelik roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases |
_version_ |
1718422341740920832 |