ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES

Perivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter o...

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Autores principales: E. G. Uchasova, O V Gruzdeva, Yu A Dyleva, E V Belik
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Lenguaje:RU
Publicado: SPb RAACI 2019
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Acceso en línea:https://doaj.org/article/33f6650dffd545e9b3251fe59ba4493a
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spelling oai:doaj.org-article:33f6650dffd545e9b3251fe59ba4493a2021-11-18T08:03:48ZROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES1563-06252313-741X10.15789/1563-0625-2019-4-633-642https://doaj.org/article/33f6650dffd545e9b3251fe59ba4493a2019-10-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1607https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XPerivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter of the vessels. Adipocytokines and chemokines, secreted from the perivascular adipose tissue, apparently have direct access to the adjacent arterial wall by diffusion, or through vasa vasorum. The present data indicate that perivascular adipose tissue plays an important role in atherosclerosis, hypertension. Recently, some studies were performed that examined the role of perivascular adipose tissue in non-atherosclerotic vascular diseases, such as neointimal formation, aortic aneurysm, arterial stiffness and vasculitis. The present review will discuss a role of perivascular adipose tissue in pathogenesis of atherosclerosis, hypertension and non-atherosclerotic vascular diseases.E. G. UchasovaO V GruzdevaYu A DylevaE V BelikSPb RAACIarticleperivascular adipose tissueadipokinescytokinesatherosclerosishypertensioncardiovascular diseasesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 21, Iss 4, Pp 633-642 (2019)
institution DOAJ
collection DOAJ
language RU
topic perivascular adipose tissue
adipokines
cytokines
atherosclerosis
hypertension
cardiovascular diseases
Immunologic diseases. Allergy
RC581-607
spellingShingle perivascular adipose tissue
adipokines
cytokines
atherosclerosis
hypertension
cardiovascular diseases
Immunologic diseases. Allergy
RC581-607
E. G. Uchasova
O V Gruzdeva
Yu A Dyleva
E V Belik
ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
description Perivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter of the vessels. Adipocytokines and chemokines, secreted from the perivascular adipose tissue, apparently have direct access to the adjacent arterial wall by diffusion, or through vasa vasorum. The present data indicate that perivascular adipose tissue plays an important role in atherosclerosis, hypertension. Recently, some studies were performed that examined the role of perivascular adipose tissue in non-atherosclerotic vascular diseases, such as neointimal formation, aortic aneurysm, arterial stiffness and vasculitis. The present review will discuss a role of perivascular adipose tissue in pathogenesis of atherosclerosis, hypertension and non-atherosclerotic vascular diseases.
format article
author E. G. Uchasova
O V Gruzdeva
Yu A Dyleva
E V Belik
author_facet E. G. Uchasova
O V Gruzdeva
Yu A Dyleva
E V Belik
author_sort E. G. Uchasova
title ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
title_short ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
title_full ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
title_fullStr ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
title_full_unstemmed ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
title_sort role of perivascular adipose tissue in the development of atherosclerotic and nonatherosclerotic diseases
publisher SPb RAACI
publishDate 2019
url https://doaj.org/article/33f6650dffd545e9b3251fe59ba4493a
work_keys_str_mv AT eguchasova roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases
AT ovgruzdeva roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases
AT yuadyleva roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases
AT evbelik roleofperivascularadiposetissueinthedevelopmentofatheroscleroticandnonatheroscleroticdiseases
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