Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient

Novel human polyomaviruses (HPyV) have been recently identified in solid organ transplant recipients. Trichodysplasia spinulosa (TS) is a rare disease associated with immunosuppression and induced by a polyomavirus (TSPyV). We report here a case of primary and disseminated TSPyV infection after kidn...

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Autores principales:	Marie-Céline Zanella, Damien Pastor, Mariet C. W. Feltkamp, Karine Hadaya, Samuel Cordey, Laurence Toutous Trellu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	trichodysplasia spinulosa polyomavirus polyomavirus trichodysplasia spinulosa transplantation kidney virus Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/34018a7a884a4b3cbc4597851bdc0e20
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spelling	oai:doaj.org-article:34018a7a884a4b3cbc4597851bdc0e202021-11-25T18:24:56ZSustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient10.3390/microorganisms91122982076-2607https://doaj.org/article/34018a7a884a4b3cbc4597851bdc0e202021-11-01T00:00:00Zhttps://www.mdpi.com/2076-2607/9/11/2298https://doaj.org/toc/2076-2607Novel human polyomaviruses (HPyV) have been recently identified in solid organ transplant recipients. Trichodysplasia spinulosa (TS) is a rare disease associated with immunosuppression and induced by a polyomavirus (TSPyV). We report here a case of primary and disseminated TSPyV infection after kidney transplantation with extensive skin lesions, sustained viremia, and high viral loads in urine specimens, anal, nasal and throat swabs, assessed via specific real-time PCR for TSPyV during a follow-up period of 32 months after transplantation. The detection of TSPyV with a high viral load in respiratory and anal swab samples is compatible with viral replication and thus may suggest potential respiratory and oro-fecal routes of transmission.Marie-Céline ZanellaDamien PastorMariet C. W. FeltkampKarine HadayaSamuel CordeyLaurence Toutous TrelluMDPI AGarticletrichodysplasia spinulosa polyomaviruspolyomavirustrichodysplasia spinulosatransplantationkidneyvirusBiology (General)QH301-705.5ENMicroorganisms, Vol 9, Iss 2298, p 2298 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	trichodysplasia spinulosa polyomavirus polyomavirus trichodysplasia spinulosa transplantation kidney virus Biology (General) QH301-705.5
spellingShingle	trichodysplasia spinulosa polyomavirus polyomavirus trichodysplasia spinulosa transplantation kidney virus Biology (General) QH301-705.5 Marie-Céline Zanella Damien Pastor Mariet C. W. Feltkamp Karine Hadaya Samuel Cordey Laurence Toutous Trellu Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient
description	Novel human polyomaviruses (HPyV) have been recently identified in solid organ transplant recipients. Trichodysplasia spinulosa (TS) is a rare disease associated with immunosuppression and induced by a polyomavirus (TSPyV). We report here a case of primary and disseminated TSPyV infection after kidney transplantation with extensive skin lesions, sustained viremia, and high viral loads in urine specimens, anal, nasal and throat swabs, assessed via specific real-time PCR for TSPyV during a follow-up period of 32 months after transplantation. The detection of TSPyV with a high viral load in respiratory and anal swab samples is compatible with viral replication and thus may suggest potential respiratory and oro-fecal routes of transmission.
format	article
author	Marie-Céline Zanella Damien Pastor Mariet C. W. Feltkamp Karine Hadaya Samuel Cordey Laurence Toutous Trellu
author_facet	Marie-Céline Zanella Damien Pastor Mariet C. W. Feltkamp Karine Hadaya Samuel Cordey Laurence Toutous Trellu
author_sort	Marie-Céline Zanella
title	Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient
title_short	Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient
title_full	Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient
title_fullStr	Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient
title_full_unstemmed	Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient
title_sort	sustained trichodysplasia spinulosa polyomavirus viremia illustrating a primary disseminated infection in a kidney transplant recipient
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/34018a7a884a4b3cbc4597851bdc0e20
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Sustained Trichodysplasia Spinulosa Polyomavirus Viremia Illustrating a Primary Disseminated Infection in a Kidney Transplant Recipient

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