Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80

Chromatin mediates transcription and DNA repair. Here, the authors show distinct roles of chromatin remodeler INO80 in expression of YY1-regulated genes and repair of DNA breaks by homologous recombination, a DNA repair pathway important for symmetrically-dividing neural progenitors.

Guardado en:
Detalles Bibliográficos
Autores principales: Jason M. Keil, Daniel Z. Doyle, Adel Qalieh, Mandy M. Lam, Owen H. Funk, Yaman Qalieh, Lei Shi, Nitesh Mohan, Alice Sorel, Kenneth Y. Kwan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/340883430271499d8929db958f2df645
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:340883430271499d8929db958f2df645
record_format dspace
spelling oai:doaj.org-article:340883430271499d8929db958f2df6452021-12-02T18:47:00ZSymmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino8010.1038/s41467-020-17551-42041-1723https://doaj.org/article/340883430271499d8929db958f2df6452020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17551-4https://doaj.org/toc/2041-1723Chromatin mediates transcription and DNA repair. Here, the authors show distinct roles of chromatin remodeler INO80 in expression of YY1-regulated genes and repair of DNA breaks by homologous recombination, a DNA repair pathway important for symmetrically-dividing neural progenitors.Jason M. KeilDaniel Z. DoyleAdel QaliehMandy M. LamOwen H. FunkYaman QaliehLei ShiNitesh MohanAlice SorelKenneth Y. KwanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jason M. Keil
Daniel Z. Doyle
Adel Qalieh
Mandy M. Lam
Owen H. Funk
Yaman Qalieh
Lei Shi
Nitesh Mohan
Alice Sorel
Kenneth Y. Kwan
Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
description Chromatin mediates transcription and DNA repair. Here, the authors show distinct roles of chromatin remodeler INO80 in expression of YY1-regulated genes and repair of DNA breaks by homologous recombination, a DNA repair pathway important for symmetrically-dividing neural progenitors.
format article
author Jason M. Keil
Daniel Z. Doyle
Adel Qalieh
Mandy M. Lam
Owen H. Funk
Yaman Qalieh
Lei Shi
Nitesh Mohan
Alice Sorel
Kenneth Y. Kwan
author_facet Jason M. Keil
Daniel Z. Doyle
Adel Qalieh
Mandy M. Lam
Owen H. Funk
Yaman Qalieh
Lei Shi
Nitesh Mohan
Alice Sorel
Kenneth Y. Kwan
author_sort Jason M. Keil
title Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_short Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_full Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_fullStr Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_full_unstemmed Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
title_sort symmetric neural progenitor divisions require chromatin-mediated homologous recombination dna repair by ino80
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/340883430271499d8929db958f2df645
work_keys_str_mv AT jasonmkeil symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT danielzdoyle symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT adelqalieh symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT mandymlam symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT owenhfunk symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT yamanqalieh symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT leishi symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT niteshmohan symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT alicesorel symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
AT kennethykwan symmetricneuralprogenitordivisionsrequirechromatinmediatedhomologousrecombinationdnarepairbyino80
_version_ 1718377672299511808