Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
Chromatin mediates transcription and DNA repair. Here, the authors show distinct roles of chromatin remodeler INO80 in expression of YY1-regulated genes and repair of DNA breaks by homologous recombination, a DNA repair pathway important for symmetrically-dividing neural progenitors.
Guardado en:
Autores principales: | Jason M. Keil, Daniel Z. Doyle, Adel Qalieh, Mandy M. Lam, Owen H. Funk, Yaman Qalieh, Lei Shi, Nitesh Mohan, Alice Sorel, Kenneth Y. Kwan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/340883430271499d8929db958f2df645 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Genome information processing by the INO80 chromatin remodeler positions nucleosomes
por: Elisa Oberbeckmann, et al.
Publicado: (2021) -
Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion
por: Lei Shi, et al.
Publicado: (2019) -
The Arp8 and Arp4 module acts as a DNA sensor controlling INO80 chromatin remodeling
por: Sandipan Brahma, et al.
Publicado: (2018) -
Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease
por: Siyeon Rhee, et al.
Publicado: (2018) -
Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability
por: Lisa Prendergast, et al.
Publicado: (2020)