Host-Induced Genome Instability Rapidly Generates Phenotypic Variation across <named-content content-type="genus-species">Candida albicans</named-content> Strains and Ploidy States
ABSTRACT Candida albicans is an opportunistic fungal pathogen of humans that is typically diploid yet has a highly labile genome tolerant of large-scale perturbations including chromosomal aneuploidy and loss-of-heterozygosity events. The ability to rapidly generate genetic variation is crucial for...
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Main Authors: | Amanda C. Smith, Meleah A. Hickman |
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Format: | article |
Language: | EN |
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American Society for Microbiology
2020
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Online Access: | https://doaj.org/article/3409c403985d4e2bb9f246e8a263d11b |
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