Deferasirox and vitamin D improves overall survival in elderly patients with acute myeloid leukemia after demethylating agents failure.

Deferasirox and vitamin D improves overall survival in elderly patients with acute myeloid leukemia after demethylating agents failure.

The prognosis of acute myeloid leukemia (AML) in elderly (≥65 years) patients is poor and treatment remains non-consensual especially for those who are not eligible for intensive therapies. Our group has shown that in vitro the iron chelator deferasirox (DFX) synergizes with vitamin D (VD) to promot...

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Autores principales: Etienne Paubelle, Florence Zylbersztejn, Sawsaneh Alkhaeir, Felipe Suarez, Céline Callens, Michaël Dussiot, Françoise Isnard, Marie-Thérèse Rubio, Gandhi Damaj, Norbert-Claude Gorin, Jean-Pierre Marolleau, Renato C Monteiro, Ivan C Moura, Olivier Hermine
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/34139b8d626449939c5c19c402e95539
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