AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle

Methyl metabolites in the one-carbon cycle, such as phosphatidylcholines and S-adenosylmethionine, play a role in hepatic triglyceride regulation. Here Kim et al. show that AhR and SHP are both involved in the expression of several key enzymes of one-carbon metabolism, with the former regulating the...

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Autores principales:	Young-Chae Kim, Sunmi Seok, Sangwon Byun, Bo Kong, Yang Zhang, Grace Guo, Wen Xie, Jian Ma, Byron Kemper, Jongsook Kim Kemper
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3414f19162614a49b09a092ddd9ca7b9
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spelling	oai:doaj.org-article:3414f19162614a49b09a092ddd9ca7b92021-12-02T15:34:27ZAhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle10.1038/s41467-018-03060-y2041-1723https://doaj.org/article/3414f19162614a49b09a092ddd9ca7b92018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03060-yhttps://doaj.org/toc/2041-1723Methyl metabolites in the one-carbon cycle, such as phosphatidylcholines and S-adenosylmethionine, play a role in hepatic triglyceride regulation. Here Kim et al. show that AhR and SHP are both involved in the expression of several key enzymes of one-carbon metabolism, with the former regulating them early after feeding and the latter inhibiting AhR at later stages.Young-Chae KimSunmi SeokSangwon ByunBo KongYang ZhangGrace GuoWen XieJian MaByron KemperJongsook Kim KemperNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Young-Chae Kim Sunmi Seok Sangwon Byun Bo Kong Yang Zhang Grace Guo Wen Xie Jian Ma Byron Kemper Jongsook Kim Kemper AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
description	Methyl metabolites in the one-carbon cycle, such as phosphatidylcholines and S-adenosylmethionine, play a role in hepatic triglyceride regulation. Here Kim et al. show that AhR and SHP are both involved in the expression of several key enzymes of one-carbon metabolism, with the former regulating them early after feeding and the latter inhibiting AhR at later stages.
format	article
author	Young-Chae Kim Sunmi Seok Sangwon Byun Bo Kong Yang Zhang Grace Guo Wen Xie Jian Ma Byron Kemper Jongsook Kim Kemper
author_facet	Young-Chae Kim Sunmi Seok Sangwon Byun Bo Kong Yang Zhang Grace Guo Wen Xie Jian Ma Byron Kemper Jongsook Kim Kemper
author_sort	Young-Chae Kim
title	AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
title_short	AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
title_full	AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
title_fullStr	AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
title_full_unstemmed	AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle
title_sort	ahr and shp regulate phosphatidylcholine and s-adenosylmethionine levels in the one-carbon cycle
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3414f19162614a49b09a092ddd9ca7b9
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AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle

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