Bacterial Quorum Sensing and Microbial Community Interactions

ABSTRACT Many bacteria use a cell-cell communication system called quorum sensing to coordinate population density-dependent changes in behavior. Quorum sensing involves production of and response to diffusible or secreted signals, which can vary substantially across different types of bacteria. In...

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Autores principales:	Rhea G. Abisado, Saida Benomar, Jennifer R. Klaus, Ajai A. Dandekar, Josephine R. Chandler
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	quorum sensing antibiotics coculture competition cooperation Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/34239f134bf540b5aeeae0b7b202b583
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spelling	oai:doaj.org-article:34239f134bf540b5aeeae0b7b202b5832021-11-15T16:00:27ZBacterial Quorum Sensing and Microbial Community Interactions10.1128/mBio.02331-172150-7511https://doaj.org/article/34239f134bf540b5aeeae0b7b202b5832018-07-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02331-17https://doaj.org/toc/2150-7511ABSTRACT Many bacteria use a cell-cell communication system called quorum sensing to coordinate population density-dependent changes in behavior. Quorum sensing involves production of and response to diffusible or secreted signals, which can vary substantially across different types of bacteria. In many species, quorum sensing modulates virulence functions and is important for pathogenesis. Over the past half-century, there has been a significant accumulation of knowledge of the molecular mechanisms, signal structures, gene regulons, and behavioral responses associated with quorum-sensing systems in diverse bacteria. More recent studies have focused on understanding quorum sensing in the context of bacterial sociality. Studies of the role of quorum sensing in cooperative and competitive microbial interactions have revealed how quorum sensing coordinates interactions both within a species and between species. Such studies of quorum sensing as a social behavior have relied on the development of “synthetic ecological” models that use nonclonal bacterial populations. In this review, we discuss some of these models and recent advances in understanding how microbes might interact with one another using quorum sensing. The knowledge gained from these lines of investigation has the potential to guide studies of microbial sociality in natural settings and the design of new medicines and therapies to treat bacterial infections.Rhea G. AbisadoSaida BenomarJennifer R. KlausAjai A. DandekarJosephine R. ChandlerAmerican Society for Microbiologyarticlequorum sensingantibioticscoculturecompetitioncooperationMicrobiologyQR1-502ENmBio, Vol 9, Iss 3 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	quorum sensing antibiotics coculture competition cooperation Microbiology QR1-502
spellingShingle	quorum sensing antibiotics coculture competition cooperation Microbiology QR1-502 Rhea G. Abisado Saida Benomar Jennifer R. Klaus Ajai A. Dandekar Josephine R. Chandler Bacterial Quorum Sensing and Microbial Community Interactions
description	ABSTRACT Many bacteria use a cell-cell communication system called quorum sensing to coordinate population density-dependent changes in behavior. Quorum sensing involves production of and response to diffusible or secreted signals, which can vary substantially across different types of bacteria. In many species, quorum sensing modulates virulence functions and is important for pathogenesis. Over the past half-century, there has been a significant accumulation of knowledge of the molecular mechanisms, signal structures, gene regulons, and behavioral responses associated with quorum-sensing systems in diverse bacteria. More recent studies have focused on understanding quorum sensing in the context of bacterial sociality. Studies of the role of quorum sensing in cooperative and competitive microbial interactions have revealed how quorum sensing coordinates interactions both within a species and between species. Such studies of quorum sensing as a social behavior have relied on the development of “synthetic ecological” models that use nonclonal bacterial populations. In this review, we discuss some of these models and recent advances in understanding how microbes might interact with one another using quorum sensing. The knowledge gained from these lines of investigation has the potential to guide studies of microbial sociality in natural settings and the design of new medicines and therapies to treat bacterial infections.
format	article
author	Rhea G. Abisado Saida Benomar Jennifer R. Klaus Ajai A. Dandekar Josephine R. Chandler
author_facet	Rhea G. Abisado Saida Benomar Jennifer R. Klaus Ajai A. Dandekar Josephine R. Chandler
author_sort	Rhea G. Abisado
title	Bacterial Quorum Sensing and Microbial Community Interactions
title_short	Bacterial Quorum Sensing and Microbial Community Interactions
title_full	Bacterial Quorum Sensing and Microbial Community Interactions
title_fullStr	Bacterial Quorum Sensing and Microbial Community Interactions
title_full_unstemmed	Bacterial Quorum Sensing and Microbial Community Interactions
title_sort	bacterial quorum sensing and microbial community interactions
publisher	American Society for Microbiology
publishDate	2018
url	https://doaj.org/article/34239f134bf540b5aeeae0b7b202b583
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_version_	1718426957829373952

Bacterial Quorum Sensing and Microbial Community Interactions

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